N-Cinnamylidene-p-methoxymethoxyaniline | 86648-87-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-Cinnamylidene-p-methoxymethoxyaniline
• CAS: 86648-87-5
• 化学式: C₁₇H₁₇NO₂
• 分子量: 267.327
• InChiKey: RJJBDRHHBLWDAW-LKKZCKFMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.09
• 重原子数：
  20.0
• 可旋转键数：
  6.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  30.82
• 氢给体数：
  0.0
• 氢受体数：
  3.0

文献信息

• Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
  申请人：BEECHAM GROUP PLC

  公开号：EP0034443A2

  公开（公告）日：1981-08-26

  The present invention provides the compounds of the formula (II): and pharmaceutically acceptable salts and cleavable esters thereof wherein RCONH is an organic acylamino group and E is a carboxy group or pharmaceutically acceptable salt or ester thereof or is a cyano group. Their preparation is described as is their use in compositions containing them. Compounds wherein RCONH is replaced by an azido group are described as useful intermediates.

  本发明提供了式(II)化合物： 及其药学上可接受的盐和可裂解酯 其中 RCONH 是有机酰氨基，E 是羧基或其药学上可接受的盐或酯或氰基。本文介绍了它们的制备方法以及在含有它们的组合物中的用途。RCONH 被叠氮基团取代的化合物被描述为有用的中间体。
• Beta-lactam compounds, their preparation and their use
  申请人：BEECHAM GROUP PLC

  公开号：EP0073100A1

  公开（公告）日：1983-03-02

  A compound of formula (I): or a pharmaceutically acceptable salt or cleavable ester thereof, wherein RCONH- represents an organic acylamino group, and E is a carboxy group or a pharmaceutically acceptable salt or C,.,o alkyl or substituted C1-10 alkyl ester thereof or is a cyano group.

  式 (I) 的化合物：或其药学上可接受的盐或可裂解酯，其中 RCONH- 代表有机酰氨基，而 E 是羧基或其药学上可接受的盐或 C，.,o 烷基或取代的 C1-10 烷基酯或氰基。
• US4407815A
  申请人：——

  公开号：US4407815A

  公开（公告）日：1983-10-04