N-(3-Isothiocyanatopropyl)-2-methylprop-2-enamide | 849150-17-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(3-Isothiocyanatopropyl)-2-methylprop-2-enamide
• CAS: 849150-17-0
• 化学式: C₈H₁₂N₂OS
• 分子量: 184.26
• InChiKey: LNJYHYJGJOCYCH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  73.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Attachment of molecules to surfaces
  申请人：Ofstead F. Ronald

  公开号：US20050074478A1

  公开（公告）日：2005-04-07

  The present invention relates to methods, reagents, and substrates that can be used for, for example, immobilizing biomolecules, such as nucleic acids and proteins. In an embodiment, the present invention relates to surfaces coated with a polymer according to the present invention. In an embodiment, the present invention relates to methods for thermochemically and/or photochemically attaching molecules to a surface at a high density.

  本发明涉及的方法、试剂和底物可用于固定生物分子，例如核酸和蛋白质。在一种实施方式中，本发明涉及涂有根据本发明的聚合物的表面。在一种实施方式中，本发明涉及将分子热化学和/或光化学地附着到表面上以高密度固定的方法。
• ATTACHMENT OF MOLECULES TO SURFACES
  申请人：Ofstead Ronald F.

  公开号：US20110009292A1

  公开（公告）日：2011-01-13

  The present invention relates to methods, reagents, and substrates that can be used for, for example, immobilizing biomolecules, such as nucleic acids and proteins. In an embodiment, the present invention relates to surfaces coated with a polymer according to the present invention. In an embodiment, the present invention relates to methods for thermochemically and/or photochemically attaching molecules to a surface at a high density.

  本发明涉及用于固定生物分子，如核酸和蛋白质的方法、试剂和底物。在一种实施方案中，本发明涉及涂有本发明中的聚合物的表面。在一种实施方案中，本发明涉及用于在高密度下热化学和/或光化学地将分子附着到表面的方法。
• Methods and reagents for preparing biomolecule-containing coatings
  申请人：Heyer M. Toni

  公开号：US20050281857A1

  公开（公告）日：2005-12-22

  Polymeric coatings that include coupled biomolecules are formed on the surface of articles, such as medical devices. A coated layer that includes a synthetic polymer including a reactive group is formed on a surface and then a biomolecule is attached to the reactive group. The synthetic polymer can be an acrylate polymer or an amine-containing polymer having pendent photoreactive groups.

  在医疗器械等物品表面形成包括耦合生物分子的聚合物涂层。在表面形成包括活性基团的合成聚合物涂层，然后将生物分子连接到活性基团上。合成聚合物可以是丙烯酸酯聚合物，也可以是具有下垂光活性基团的含胺聚合物。
• METHODS AND REAGENTS FOR PREPARING BIOMOLECULE-CONTAINING COATINGS
  申请人：Heyer Toni M.

  公开号：US20120010707A1

  公开（公告）日：2012-01-12

  Polymeric coatings that include coupled biomolecules are formed on the surface of articles, such as medical devices. A coated layer that includes a synthetic polymer including a reactive group is formed on a surface and then a biomolecule is attached to the reactive group. The synthetic polymer can be an acrylate polymer or an amine-containing polymer having pendent photoreactive groups.
• US7309593B2
  申请人：——

  公开号：US7309593B2

  公开（公告）日：2007-12-18