Methylphosphinoyl-ethene | 167896-37-9

• 分子结构分类: 有机化合物 - 有机磷化合物 - 有机膦及其衍生物
• 英文名称: Methylphosphinoyl-ethene
• 英文别名: 1-methylphosphonoylethene
• CAS: 167896-37-9
• 化学式: C₃H₇OP
• 分子量: 90.0617
• InChiKey: YIUULECFVOJSME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  5
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  丙烯酸甲酯（MA） 、 Methylphosphinoyl-ethene 生成 3-(Methyl-vinyl-phosphinoyl)-propionic acid methyl ester
  参考文献：
  名称：

  First synthesis of secondary P-alkenyl and P-alkynyl phosphine oxides

  摘要：

  A general method for preparing secondary P-alkenyl and P-alkynyl phosphine oxides, compounds unknown so far, involves the condensation of the vinyl Grignard reagent or lithium acetylide on P-chloroaminophosphines followed by acidic hydrolysis of the corresponding vinyl- or ethynylaminophosphines on a solid acid (Amberlyst 15). The few reported chemical properties are mainly related to the strong PH bond activation. Of special interest is the addition of a secondary vinylphosphine oxyde derivative on methyl acrylate which occurs at room temperature without any catalyst.

  DOI：

  10.1016/0040-4039(95)00761-z
• 作为产物：
  描述：

  N-(ethenyl-methylphosphanyl)-N-ethylethanamine 在 Amberlyst 15 、 水 作用下， 以 四氢呋喃 为溶剂， 生成 Methylphosphinoyl-ethene
  参考文献：
  名称：

  First synthesis of secondary P-alkenyl and P-alkynyl phosphine oxides

  摘要：

  A general method for preparing secondary P-alkenyl and P-alkynyl phosphine oxides, compounds unknown so far, involves the condensation of the vinyl Grignard reagent or lithium acetylide on P-chloroaminophosphines followed by acidic hydrolysis of the corresponding vinyl- or ethynylaminophosphines on a solid acid (Amberlyst 15). The few reported chemical properties are mainly related to the strong PH bond activation. Of special interest is the addition of a secondary vinylphosphine oxyde derivative on methyl acrylate which occurs at room temperature without any catalyst.

  DOI：

  10.1016/0040-4039(95)00761-z

文献信息

• First synthesis of secondary P-alkenyl and P-alkynyl phosphine oxides
  作者：Gnon Baba、Jean-François Pilard、Khalid Tantaoui、Annie-Claude Gaumont、Jean-Marc Denis

  DOI：10.1016/0040-4039(95)00761-z

  日期：1995.6

  A general method for preparing secondary P-alkenyl and P-alkynyl phosphine oxides, compounds unknown so far, involves the condensation of the vinyl Grignard reagent or lithium acetylide on P-chloroaminophosphines followed by acidic hydrolysis of the corresponding vinyl- or ethynylaminophosphines on a solid acid (Amberlyst 15). The few reported chemical properties are mainly related to the strong PH bond activation. Of special interest is the addition of a secondary vinylphosphine oxyde derivative on methyl acrylate which occurs at room temperature without any catalyst.