9-Octadecenoic acid, 12-(sulfooxy)-, (Z)- | 32430-00-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 9-Octadecenoic acid, 12-(sulfooxy)-, (Z)-
• 英文别名: (Z)-12-sulfooxyoctadec-9-enoic acid
• CAS: 32430-00-5
• 化学式: C₁₈H₃₄O₆S
• 分子量: 378.5
• InChiKey: CYKFQSXTIVGYDT-XFXZXTDPSA-N

物化性质

• 密度：
  1.116±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  25
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  109
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• INHIBITION OF PHOSPHATASE ACTIVITY OF SOLUBLE EPOXIDE HYDROLASE AMINO TERMINUS AND USES THEREOF
  申请人：Hammock Bruce D.

  公开号：US20090215894A1

  公开（公告）日：2009-08-27

  Inhibitors of the phosphatase activity of soluble epoxide hydrolase (sEH) are provided and are useful for in the treatment of diseases. These Inhibitors are based on derivatives of various epoxide hydrolase substrates that mimic the enzyme substrate so that there Is stable Interaction with the enzyme catalytic site. These inhibitors are potentially useful for the treatment of hypertension, vascular inflammation, renal inflammation, and lung disease.