3-苯基-3,5-环己二烯-1,1,2,2-四胺 | 71625-27-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3-苯基-3,5-环己二烯-1,1,2,2-四胺
• 英文名称: 3,3',4,4'-biphenyltetramine
• 英文别名: tetraminobiphenyl；diaminobenzidine；2,2',3,3'-Tetraamino-biphenyl；[1,1'-Biphenyl]-2,2',3,3'-tetramine；3-(2,3-diaminophenyl)benzene-1,2-diamine
• CAS: 71625-27-9
• 化学式: C₁₂H₁₄N₄
• 分子量: 214.27
• InChiKey: LQVQDAHYOABYHD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  104
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-ferrocenyl-2-phenylethane-1,2-dione 、 3-苯基-3,5-环己二烯-1,1,2,2-四胺 在 potassium carbonate 、 sodium sulfite 作用下， 以 乙醇 、 水 为溶剂， 以77%的产率得到ferrocenylphenyl-6-(3',4'-diaminophenyl)quinoxaline
  参考文献：
  名称：

  Synthesis and redox properties of ferrocenylquinoxalines

  摘要：

  The ferrocenyl 1,2-diketone [(C5H5)Fe(C5H4)COCOPh] when condensed with aromatic 1,2-diamines forms a range of ferrocenyl-substituted quinoxalines: when the diamine is unsymmetrically substituted the quinoxaline is formed as a mixture of two regio-isomers, which can in some cases be separated by careful chromatography. Electrochemical studies show that these present ferrocenylquinoxalines undergo the expected reversible one-electron oxidation centred on the ferrocenyl moiety and a two-electron reduction process centred on the quinoxalyl fragment, which is accompanied by chemical complications. The oxidation of the ferrocenyl group occurs at potentials slightly higher than that of unsubstituted ferrocene (by about 100-150 mV, depending on the substituents) indicating that the quinoxalyl substituent is slightly electron-withdrawing with respect to ferrocene. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0277-5387(98)00223-x
• 作为产物：
  描述：

  1-碘-2,3-二硝基-苯 在 盐酸 、 4-硝基甲苯 、 铜 、 tin(ll) chloride 作用下， 以 乙醇 为溶剂， 生成 3-苯基-3,5-环己二烯-1,1,2,2-四胺
  参考文献：
  名称：

  Dieteren,H.M.L.; Koningsberger,C., Recueil des Travaux Chimiques des Pays-Bas, 1963, vol. 82, p. 5 - 16

  摘要：

  DOI：

文献信息

• [EN] RUTHENIUM (II) COMPLEXES FOR THE TREATMENT OF TUMORS<br/>[FR] COMPLEXES DE RUTHENIUM (II) UTILES DANS LE TRAITEMENT DES TUMEURS
  申请人：UNIV EDINBURGH

  公开号：WO2004096819A1

  公开（公告）日：2004-11-11

  Ruthenium (II) compounds of formula (I) are useful in the treatment and/or prevention of cancer.

  Ruthenium (II)化合物的化学式(I)在癌症的治疗和/或预防中很有用。
• Method for Producing Aromatic and Heteroaromatic Carboxylic Acids, Carboxylic Acid Esters and Carboxylic Acid Amides
  申请人：Challand Nina

  公开号：US20110172456A1

  公开（公告）日：2011-07-14

  Process for the preparation of aromatic and heteroaromatic carboxylic acids, carboxylic acid esters and carboxamides by the reaction of aromatic or heteroaromatic halides R—X n , in which n=integer from 1 to 6, R=substituted or unsubstituted and aromatic or heteroaromatic radical and X=chlorine, bromine or iodine atom, with carbon monoxide and water, ammonia, alcohols or amines in the presence of bases and zero-valent or divalent palladium compounds and bidentate diphosphanes or complexes of zero-valent or divalent palladium with bidentate diphosphanes, in which use is made of bidentate diphosphanes (R 1 —)(R 2 —)P—Y—P(—R 3 )(—R 4 ) in which R 1 to R 4 =unsubstituted aryl radicals or aryl radicals substituted with at least one radical exhibiting a positive resonance effect or a positive inductive effect, or unsubstituted or substituted cycloalkyl radicals, and Y=hydrocarbon group with a total of 2 to 20 carbon atoms, in which at least one of the carbon atoms carries only one or no hydrogen atom as substituent; except for the reaction of 4-bromo-3-difluoromethyl-1-methylpyrazole with 2-(3,4,5-trifluorophenyl)aniline and carbon monoxide to give N-[2-(3,4,5-trifluorophenyl)phenyl]-3-difluoromethyl-1-methylpyrazole-4-carboxamide.

  用芳香或杂芳卤代烃R—Xn（其中n=1到6的整数，R=取代或未取代的芳香或杂芳基团，X=氯、溴或碘原子）与一氧化碳和水、氨、醇或胺在碱存在下，以及零价或二价钯化合物和双膦或零价或二价钯与双膦的配合物反应，制备芳香和杂芳羧酸、羧酸酯和羧酰胺的方法的过程，其中使用双膦(R1—)(R2—)P—Y—P(—R3)(—R4)，其中R1到R4=未取代芳基基团或带有至少一个正共振效应或正归纳效应的基团的取代芳基基团，或未取代或取代的环烷基基团，Y=含有2到20个碳原子的碳氢基团，其中至少一个碳原子只携带一个或没有氢原子作为取代基；但不包括4-溴-3-二氟甲基-1-甲基吡唑与2-(3,4,5-三氟苯基)苯胺和一氧化碳反应形成N-[2-(3,4,5-三氟苯基)苯基]-3-二氟甲基-1-甲基吡唑-4-羧酰胺。
• [EN] A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL<br/>[FR] NOUVEAU PROCEDE CATALYTIQUE DE PRODUCTION DE 3,3', 4,4'-TETRAMINOBIPHENYLE
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2005092839A1

  公开（公告）日：2005-10-06

  This invention relates to a process for the production of 3,3’, 4,4’-tetraminobiphenyl (TAB) of formula (1) from non-carcinogenic raw materials, employing Suzuki type biaryl coupling as the key step. sMore particularly, it relates to a three steps process for the production of TAB comprising biaryl aryl coupling of 2-nitro-4-bromoacetanilide (NBA) of formula (2) catalyzed by sulfilimine based palladacycles as catalysts followed by the basic hydrolysis of acetyl group and the reduction of nitro groups with conventional reducing agents.

  这项发明涉及一种从非致癌原料制备3,3'，4,4'-四氨基联苯（TAB）的方法，其关键步骤是采用铃木偶联反应。更具体地说，它涉及一种三步法生产TAB的过程，包括以磺亚胺基钯环化合物为催化剂催化2-硝基-4-溴乙酰苯胺（NBA）的偶联反应，随后进行乙酰基碱性水解和用传统还原剂还原硝基基团。
• AROMATIC HALOSULFONYL ISOCYANATE COMPOSITIONS
  申请人：Yeager Gary William

  公开号：US20090242831A1

  公开（公告）日：2009-10-01

  The present invention provides a monomer composition comprising an aromatic halosulfonyl isocyanate having structure I wherein “m” is an integer from 2 to 5; “n” is an integer from 1 to 5; Ar is a C 3 -C 40 aromatic radical which is free of aliphatic carbon-hydrogen bonds; and X is halogen. The monomer compositions comprising aromatic halosulfonyl isocyanate I are useful in the preparation of polymeric materials useful as membranes.

  本发明提供一种单体组合物，其包括具有结构I的芳香族卤代磺酰基异氰酸酯，其中“m”为2至5的整数；“n”为1至5的整数；Ar为不含脂肪族碳氢键的C3-C40芳香基团；X为卤素。包含芳香族卤代磺酰基异氰酸酯I的单体组合物在制备作为膜的聚合材料中非常有用。
• Bridged p-phenylenediamines
  申请人：——

  公开号：US20040199018A1

  公开（公告）日：2004-10-07

  p-Phenylenediamines and derivatives thereof connected by polyoxaalkyl bridges to form dimers are highly suitable developer substances in oxidation hair colors. The bridged p-phenylenediamines are represented by the general formula (I) 1 in which (B) is a polyoxaalkyl bridge having at least two oxygen atoms; X and Y independently of one another are H, Cl, F or a C 1 -C 4 alkyl, aminoalkyl, alkoxy, C 2 -C 4 dihydroxyalkyl, C 1 -C 4 monohydroxyalkyl or C 2 -C 4 alkenyl group; and R1, R2, R3, and R4 independently of one another are H or a C 1 -C 4 alkyl, C 1 -C 4 monohydroxyalkyl or C 2 -C 4 dihydroxyalkyl group, and acid addition salts derived therefrom. A process for the preparation and a method of use of the bridged p-phenylenediamines of formula (I) are also disclosed.

  p-苯二胺及其衍生物通过聚氧烷基桥连接形成二聚体，在氧化染发剂中作为开发剂物质非常适用。桥接的p-苯二胺由通式（I）1表示，其中（B）是具有至少两个氧原子的聚氧烷基桥；X和Y独立地为H、Cl、F或C1-C4烷基、氨基烷基、烷氧基、C2-C4双羟基烷基、C1-C4单羟基烷基或C2-C4烯基基团；R1、R2、R3和R4独立地为H或C1-C4烷基、C1-C4单羟基烷基或C2-C4双羟基烷基团，并且可以得到其酸加成盐。还公开了制备桥接的p-苯二胺通式（I）的方法和使用方法。