(RS)-1,1,1-trifluoro-2-(4-trifluoromethoxyphenyl) propan-3-ol | 118752-94-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (RS)-1,1,1-trifluoro-2-(4-trifluoromethoxyphenyl) propan-3-ol
• 英文别名: 3,3,3-Trifluoro-2-[4-(trifluoromethoxy)phenyl]propan-1-ol
• CAS: 118752-94-6
• 化学式: C₁₀H₈F₆O₂
• 分子量: 274.163
• InChiKey: XHYVMPLTLUKJLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• Ether compounds, process for their preparation, compositions containing the same and use thereof
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0240978A2

  公开（公告）日：1987-10-14

  Ether compounds represented by the following general formula (I), their production and insecticidal and/or acaricidal compositions containing it as an active ingredient: wherein R, and R2, which may be identical or different, represent a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl, lower haloalkoxyl, lower alkenyl or lower alkenyloxyl group, or represent, taken together, methylenedioxy, lower alkylene, ethyleneoxy or lower alkylethyleneoxy group; R3 represents a hydrogen or fluorine atom; R4 represents a hydrogen or halogen atom or a lower alkyl, lower haloalkyl, lower alkoxyl or lower haloalkoxyl group; m represents an integer of 1 or 2; Y represents an oxygen or sulfur atom or a group represented by the formula -CH2-or -NH-; and Z represents a nitrogen atom or a group represented by the formula -CH =, and starting materials.

  由以下通式(I)代表的醚类化合物、其生产以及含有该化合物作为活性成分的杀虫和/或杀螨剂组合物： 其中，R 和 R2（可以相同或不同）代表氢原子或卤素原子或低级烷基、低级卤代烷基、低级烷氧基、低级卤代烷氧基、低级烯基或低级烯酰氧基，或同时代表亚甲基二氧基、低级亚烷基、亚乙基氧基或低级亚烷基乙氧基；R3 代表氢原子或氟原子；R4 代表氢原子或卤素原子或低级烷基、低级卤代烷基、低级烷氧基或低级卤代烷氧基；m 代表 1 或 2 的整数；Y 代表氧原子或硫原子或由式 -CH2- 或 -NH- 代表的基团；Z 代表氮原子或由式 -CH = 代表的基团，以及起始原料。
• Process for intermediates for insecticidal compounds
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0280383A1

  公开（公告）日：1988-08-31

  The invention provides novel compounds of formula I, useful as intermediates for insecticidal ethers, wherein W represents 1 to 4 substituents selected from halo, alkyl, alkoxy, haloalkyl, haloalkoxy and alkoxyalkyl, or W represents a bidentate alkylene or alkylenedioxy group linking adjacent carbon atoms, X represents fluoroalkyl, and Y is selected from chlorine, bromine and alkoxy; and a process for preparing said ethers. The compounds of formula I are prepared by reacting a ketone of formula: with a phosphonium salt of formula Hal⁻ (Q)₃P⁺-CH₂-Y, where Hal⁻ represents a halide ion and Q represents alkyl or aryl.

  本发明提供了可用作杀虫醚中间体的新型式 I 化合物，其中 W 代表 1 至 4 个选自卤代、烷基、烷氧基、卤代烷基、卤代烷氧基和烷氧基烷基的取代基，或 W 代表连接相邻碳原子的双叉亚烷基或亚烷基二氧基基团，X 代表氟代烷基，Y 选自氯、溴和烷氧基；以及制备所述醚的工艺。 式 I 化合物通过使式：的酮与式 Hal- (Q)₃P⁺-CH₂-Y 的鏻盐反应制备，其中 Hal- 代表卤离子，Q 代表烷基或芳基。
• Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0545891A2

  公开（公告）日：1993-06-09

  The present invention relates to aldehyde compounds represented by the general formula (I) wherein R₁ and R₂, which may be identical or different, represent a hydrogen or halogen atom or a C₁₋₅ alkyl, C₁₋₅-haloalkyl, C₁₋₅-alkoxyl, C₁₋₅-haloalkoxyl, C₂₋₅-alkenyl or C₂₋₅-alkenyloxyl group, or represent, taken together, a methylenedioxy, C₃₋₄-alkylene, ethyleneoxy or C₁₋₅-alkylethyleneoxy group with the proviso that when R₁ and R₂ are identical they are not hydrogen atoms. These compounds are valuable intermediates for the production of insecticidal and/or acaricidal ether compounds.

  本发明涉及通式 (I) 所代表的醛化合物 其中 R₁ 和 R₂ 可以相同或不同，代表氢原子或卤素原子或 C₁₋₅ 烷基、C₁₋₅-卤代烷基、C₁₋₅-烷氧基、C₁₋₅-卤代烷氧基、C₂₋₅-烯基或 C₂₋₅-烯氧基、或共同代表亚甲基二氧基、C₃₋₄-亚烷基、乙烯氧基或 C₁₋₅-烷基乙烯氧基，但当 R₁ 和 R₂ 相同时，它们不是氢原子。 这些化合物是生产杀虫和/或杀螨醚化合物的重要中间体。
• US4840971A
  申请人：——

  公开号：US4840971A

  公开（公告）日：1989-06-20
• US4891450A
  申请人：——

  公开号：US4891450A

  公开（公告）日：1990-01-02