丁二醇丙酸酯 | 91171-54-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 丁二醇丙酸酯
• 英文名称: Butylene glycol propionate
• 英文别名: butane-1,4-diol;propanoic acid
• CAS: 91171-54-9
• 化学式: C7H16O4
• 分子量: 164.2
• InChiKey: GUXKPDWOPIQSCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.23
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• PROCESS FOR PREPARING 1,4-BUTANDIOL MONITRATE
  申请人：Hack Achim

  公开号：US20100137599A1

  公开（公告）日：2010-06-03

  The present invention relates to a process for the preparation of 1,4-butanediol mononitrate as intermediate for large scale preparation of high purity nitrooxybutyl ester of pharmaceutically active compounds.

  本发明涉及一种制备1,4-丁二醇单硝酸酯的方法，作为制备高纯度药用活性化合物硝氧基丁酯的中间体的大规模制备。
• TOPICAL COMPOSITION COMPRISING NATURAL INGREDIENTS FOR BRUISING OR HEMATOMA HEALING ON SKIN AND USE THEREOF
  申请人：Amphora Holdings, Inc.

  公开号：EP3108877A1

  公开（公告）日：2016-12-28

  A topical composition is provided that comprises an organic liquid with enzymes, an anti-inflammatory and a topical analgesic for healing bruises or hematomas caused by contusions or lesions on tissues or resulting from illnesses. The organic liquid with enzymes can include Pyrus Malus (apple), the anti-inflammatory can include sesquiterpene lactone (arnica), and the topical analgesic can included menthol, chamomile, ginger, or Aloe Vera. The topical composition can be used to alleviate the hematoma or bruise produced by illness, particularly to disaggregate the hematoma, lower the amount of discoloration of the hematoma or bruise, decrease the amount of pain associated with the hematoma or bruise, and/or decrease inflammation associated with the hematoma or bruise.

  提供了一种外用组合物，其中包括一种含酶的有机液体、一种消炎剂和一种外用镇痛剂，用于愈合因组织挫伤或病变或疾病引起的瘀伤或血肿。含酶的有机液体可包括苹果，消炎药可包括倍半萜内酯（山金车），局部镇痛药可包括薄荷脑、甘菊、生姜或芦荟。外用组合物可用于缓解因疾病产生的血肿或瘀伤，特别是分解血肿，降低血肿或瘀伤的变色量，减少与血肿或瘀伤有关的疼痛量，和/或减少与血肿或瘀伤有关的炎症。
• Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
  申请人：Laboratory Skin Care, Inc.

  公开号：US10350168B2

  公开（公告）日：2019-07-16

  Dermal delivery compositions are provided. Aspects of the dermal delivery compositions include the presence of active agent-calcium phosphate particle complexes, where these complexes include uniform, rigid, spherical nanoporous calcium phosphate particles associated with one or more active agents. Also provided are methods of using the compositions in active agent delivery applications.

  提供了皮肤给药组合物。皮肤给药组合物的各个方面包括活性剂-磷酸钙颗粒复合物的存在，其中这些复合物包括与一种或多种活性剂相关联的均匀、硬质、球形纳米多孔磷酸钙颗粒。此外，还提供了在活性剂递送应用中使用这些组合物的方法。
• Use of copolymers based on acrylamidoalkylsulfonic acids as thickeners in preparations comprising organic solvents
  申请人：Clariant GmbH

  公开号：US20030004241A1

  公开（公告）日：2003-01-02

  The invention relates to the use of copolymers consisting essentially of a1) 1 to 50% by weight of the repeat structural unit of the formula (1) 1 where n is an integer from 2 to 9 or a2) 1 to 50% by weight of a mixture of the repeat structural unit of the formula (1) and of the repeat structural unit of the formula (2) 2 where R, R 1 and R 2 may be identical or different and are hydrogen or a linear or branched alkyl or alkenyl group having in each case 1 to 30 carbon atoms, and b) 49.99 to 98.99% by weight of the repeat structural unit of the formula (3) 3 in which R 3 is hydrogen, methyl or ethyl, Z is (C 1 -C 8 )-alkylene and X is an ammonium, alkali metal or alkaline earth metal ion and c) 0.01 to 8% by weight of crosslinking structures which originate from monomers having at least two olefinic double bonds, as thickeners in preparations comprising organic solvents.

  本发明涉及共聚物的使用，共聚物主要包括 a1) 1 至 50%（按重量计）的式（1）重复结构单元 1 其中 n 为 2 至 9 的整数，或 a2) 按重量计，1-50%的式(1)重复结构单元和式(2)重复结构单元的混合物 2 其中 R 1 和 R 2 可以相同或不同，并且是氢或线性或支链烷基或烯基，在每种情况下具有 1 至 30 个碳原子，以及 b) 49.99% 至 98.99% （按重量计）的式（3）重复结构单元 3 其中 R 3 是氢、甲基或乙基，Z 是（C 1 -C 8 烷烯，X 是铵、碱金属或碱土金属离子，以及 c) 0.01%至 8%（按重量计）的交联结构，其来源于至少有两个烯烃双键的单体，在含有有机溶剂的制剂中用作增稠剂。
• PROCESS FOR PREPARING 1,4-BUTANDIOL MONONITRATE
  申请人：Nicox S.A.

  公开号：EP2170803A1

  公开（公告）日：2010-04-07