N-(2-hydroxyethyl)-morpholine betaine | 14758-52-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: N-(2-hydroxyethyl)-morpholine betaine
• 英文别名: 2-[4-(2-Hydroxyethyl)morpholin-4-ium-4-yl]acetate
• CAS: 14758-52-2
• 化学式: C₈H₁₅NO₄
• 分子量: 189.211
• InChiKey: QSLMMBIFHDFOJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  69.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-oxo-3,9-dioxa-6-aza-spiro[5,5]-undecane chloride 在 anion-exchange resin 作用下， 以 水 为溶剂， 生成 N-(2-hydroxyethyl)-morpholine betaine
  参考文献：
  名称：

  Vieles,P.; Galsomias,J., Bulletin de la Societe Chimique de France, 1967, p. 1598 - 1603

  摘要：

  DOI：

文献信息

• STABILIZATION OF METABOLICALLY-ACTIVE CELLS IN A BLOOD SAMPLE AT AMBIENT TEMPERATURES
  申请人：Biomatrica, Inc.

  公开号：EP3155091A1

  公开（公告）日：2017-04-19
• METHODS AND COMPOSITIONS FOR STABILIZATION OF NUCLEIC ACIDS IN A BLOOD SAMPLE AT AMBIENT TEMPERATURES
  申请人：Biomatrica, Inc.

  公开号：EP3155395B1

  公开（公告）日：2021-06-02
• METHODS FOR THE CHARACTERIZATION OF FLUID
  申请人：NextGen Jane, Inc.

  公开号：EP4051109A1

  公开（公告）日：2022-09-07
• METHODS AND SYSTEMS FOR MENSTRUALOME ANALYSIS
  申请人：NextGen Jane, Inc.

  公开号：EP4051127A1

  公开（公告）日：2022-09-07
• Stabilization of Non-Denatured Polypeptides, Nucleic Acids, and Exosomes in a Blood Sample at Ambient Temperatures
  申请人：Biomatrica, Inc.

  公开号：US20170198335A1

  公开（公告）日：2017-07-13

  Provided herein are formulations for the stabilization of one or more polypeptide or nucleic acid molecule in a native, non-denatured state at ambient temperatures. Also provided are compositions, articles of manufacture, kits and methods for substantially stable storage of one or more polypeptide or nucleic acid molecule in a native, non-denatured, and/or functionally active conformation substantially free on intracellular polypeptides and nucleic acids at ambient temperatures are provided. Also provided are formulations for the stabilization of one or more exosome at ambient temperatures, and compositions, articles of manufacture, kits and methods of use.