(2R,3R,4S,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2-methoxy-3-(R)-oxiranyl-tetrahydro-pyran | 134268-80-7

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: (2R,3R,4S,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2-methoxy-3-(R)-oxiranyl-tetrahydro-pyran
• CAS: 134268-80-7
• 化学式: C₂₁H₄₄O₅Si₂
• 分子量: 432.748
• InChiKey: QXQZBSUKLZXHRF-VPAKFMSCSA-N

反应信息

• 作为反应物：
  描述：

  (2R,3R,4S,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2-methoxy-3-(R)-oxiranyl-tetrahydro-pyran 、 3,4,6-tri-O-benzyl-1-tributylstannyl-D-glucal 在 正丁基锂 、 三氟化硼乙醚 作用下， 生成 (R)-2-((4R,5S,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-5,6-dihydro-4H-pyran-2-yl)-1-[(2S,3S,4R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2-methoxy-tetrahydro-pyran-3-yl]-ethanol
  参考文献：
  名称：

  Synthesis of C-glycosides: Boron trifluoride etherate-promoted opening of epoxides by anomeric anions

  摘要：

  Lithiated glucals and higher order cuprate reagents derived from alpha- and B-2-deoxy-glycosyl lithium anions react efficiently with representative epoxides in the presence of boron trifluoride etherate.

  DOI：

  10.1016/s0040-4039(00)74882-9