vinyl-carbamic acid oxiranylmethyl ester | 2638-91-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: vinyl-carbamic acid oxiranylmethyl ester
• 英文别名: oxiran-2-ylmethyl N-ethenylcarbamate
• CAS: 2638-91-7
• 化学式: C₆H₉NO₃
• mdl: MFCD19221946
• 分子量: 143.142
• InChiKey: PNIOYHHIDHQBIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  50.9
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Biomedical devices
  申请人：Linhardt Jeffrey G.

  公开号：US20100317817A1

  公开（公告）日：2010-12-16

  Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a random copolymer comprising hydrophilic units and hydrophobic units, wherein the random copolymer has at least one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (“RAFT”) agent are disclosed.

  本发明公开了一种生物医学装置，例如由混合物聚合产物形成的随机共聚物接触镜，其中该混合物包括（a）包含亲水基团和疏水基团的随机共聚物，其中该随机共聚物至少具有可逆加成断裂链转移（“RAFT”）剂的硫代碳酰硫片段。
• Coating solutions comprising segmented reactive block copolymers
  申请人：BAUSCH & LOMB INCORPORATED

  公开号：EP2597113A1

  公开（公告）日：2013-05-29

  This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.

  本发明的目的是对设备进行表面处理。表面处理包括通过末端官能化表面活性剂材料的反应官能性与聚合物基材上单体单元的互补表面反应官能性反应，将反应性分段嵌段共聚物附着在基材表面。本发明还涉及一种表面改性的医疗设备，其中包括隐形眼镜、眼内镜片、血管支架、phakic 眼内镜片、apakic 眼内镜片、角膜植入物、导管、植入物等，其表面由这种方法制成。
• Contact lens packaging solutions containing hydrophilic polymers endcapped with a hydrophilic and a hydrophobic group
  申请人：Bausch & Lomb Incorporated

  公开号：US11492189B2

  公开（公告）日：2022-11-08

  A packaging system for the storage of an ophthalmic device is disclosed. The packaging system comprises a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising one or more hydrophilic polymers or copolymers comprising hydrophilic units and endcapped with a hydrophobic end group and a hydrophilic end group, wherein the solution has an osmolality of at least about 200 mOsm/kg, a pH of about 6 to about 9 and is heat sterilized.

  本发明公开了一种用于储存眼科设备的包装系统。 该包装系统包括一个密封容器，其中装有一个或多个未使用的眼科器械，该容器浸没在水性包装溶液中，该溶液由一种或多种亲水聚合物或共聚物组成，这些聚合物由亲水单元组成，并以疏水端基和亲水端基封端，其中溶液的渗透压至少约为 200 mOsm/kg，pH 值约为 6 至 9，并经过热消毒。
• SURFACE TREATMENT OF MEDICAL DEVICE
  申请人：BAUSCH & LOMB INCORPORATED

  公开号：EP1572261B1

  公开（公告）日：2008-07-30
• PACKAGING SOLUTIONS
  申请人：Bausch & Lomb Incorporated

  公开号：EP2237699A1

  公开（公告）日：2010-10-13