5,7,13,15-tetrahydroxy-1,3,5,7,9,11,13,15-octaisopropyltricyclo[9.5.1.1^3,9]octasiloxane | 1029130-95-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5,7,13,15-tetrahydroxy-1,3,5,7,9,11,13,15-octaisopropyltricyclo[9.5.1.1^3,9]octasiloxane
• CAS: 1029130-95-7
• 化学式: C₂₄H₆₀O₁₄Si₈
• 分子量: 797.416
• InChiKey: HYAKQFNGDKIIPM-IZTRXORCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.95
• 重原子数：
  46.0
• 可旋转键数：
  8.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  173.22
• 氢给体数：
  4.0
• 氢受体数：
  14.0

反应信息

• 作为反应物：
  描述：

  1,3-dichloro-1,3-diisopropyl-1,3-diphenyldisiloxane 、 5,7,13,15-tetrahydroxy-1,3,5,7,9,11,13,15-octaisopropyltricyclo[9.5.1.1^3,9]octasiloxane 在 吡啶 作用下， 反应 3.0h， 以9%的产率得到9,11,21,23-tetraphenyl-1,3,5,7,9,11,13,15,17,19,21,23-dodecaisopropylpentacyclo[17.5.1.1^3,17.1^5,15.1^7,13]dodecasiloxane
  参考文献：
  名称：

  Pentacyclic Laddersiloxane

  摘要：

  A novel method which effects ring extension of the ladder oligosilsesquioxanes was developed. By applying this method, we synthesized the first functionalized tricyclic laddersiloxanes and pentacyclic laddersiloxane. The reaction of (i-PrSi(OH)O)4 with (i-PrPhClSiO)2 in pyridine gave the tetraphenyl tricyclic laddersiloxane. Following dephenylchlorination with AlCl3/HCl, and hydrolysis enabled us to isolate the tetrahydroxyl tricyclic laddersiloxane in good yield. We repeated the similar reaction from this tetrahydroxyl laddersiloxane, and the first pentacyclic laddersiloxane was obtained. The structures of the tetraphenyl and tetrahydroxyl tricyclic laddersiloxanes, and pentacyclic laddersiloxane were determined by X-ray crystallography.

  DOI：

  10.1021/ja0173876
• 作为产物：
  描述：

  5,7,13,15-tetrachloro-1,3,5,7,9,11,13,15-octaisopropyltricyclo[9.5.1.1^3,9]octasiloxane 在 吡啶 、 水 作用下， 以 乙醚 为溶剂， 反应 3.5h， 以19%的产率得到5,7,13,15-tetrahydroxy-1,3,5,7,9,11,13,15-octaisopropyltricyclo[9.5.1.1^3,9]octasiloxane
  参考文献：
  名称：

  Pentacyclic Laddersiloxane

  摘要：

  A novel method which effects ring extension of the ladder oligosilsesquioxanes was developed. By applying this method, we synthesized the first functionalized tricyclic laddersiloxanes and pentacyclic laddersiloxane. The reaction of (i-PrSi(OH)O)4 with (i-PrPhClSiO)2 in pyridine gave the tetraphenyl tricyclic laddersiloxane. Following dephenylchlorination with AlCl3/HCl, and hydrolysis enabled us to isolate the tetrahydroxyl tricyclic laddersiloxane in good yield. We repeated the similar reaction from this tetrahydroxyl laddersiloxane, and the first pentacyclic laddersiloxane was obtained. The structures of the tetraphenyl and tetrahydroxyl tricyclic laddersiloxanes, and pentacyclic laddersiloxane were determined by X-ray crystallography.

  DOI：

  10.1021/ja0173876