dimethoxy-5,7 (acetoxymethyl)-4 coumarine | 111507-73-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: dimethoxy-5,7 (acetoxymethyl)-4 coumarine
• 英文别名: (5,7-Dimethoxy-2-oxochromen-4-yl)methyl acetate
• CAS: 111507-73-4
• 化学式: C₁₄H₁₄O₆
• 分子量: 278.262
• InChiKey: PLNSRHDWXQEKAH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  乙酸酐 、 dimethoxy-5,7 (hydroxymethyl)-4 coumarine 在 三乙胺 作用下， 反应 2.0h， 以98%的产率得到dimethoxy-5,7 (acetoxymethyl)-4 coumarine
  参考文献：
  名称：

  Ramiandrasoa, F.; Kunesch, N.; Kunesch, G., Bulletin de la Societe Chimique de France, 1987, # 1, p. 177 - 180

  摘要：

  DOI：

文献信息

• PHOTOCLEAVABLE PROTECTING GROUPS
  申请人：Barone Anthony D.

  公开号：US20090076295A1

  公开（公告）日：2009-03-19

  Novel compounds are provided, which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Y, wherein Y is a chemical structure as shown in FIG. 1 . Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region of the support, using the protected compounds described above.
• Photocleavable Protecting Groups
  申请人：Barone Anthony D.

  公开号：US20100324266A1

  公开（公告）日：2010-12-23

  Novel compounds are provided, which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Y, wherein Y is a chemical structure as shown in FIG. 1 . Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region of the support, using the protected compounds described above.
• Ramiandrasoa, F.; Kunesch, N.; Kunesch, G., Bulletin de la Societe Chimique de France, 1987, # 1, p. 177 - 180
  作者：Ramiandrasoa, F.、Kunesch, N.、Kunesch, G.、Poisson, J.

  DOI：——

  日期：——