ethyl 4-[2-(3-hydroxybutyl)phenyl]butanoate | 910661-50-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 4-[2-(3-hydroxybutyl)phenyl]butanoate
• CAS: 910661-50-6
• 化学式: C₁₆H₂₄O₃
• 分子量: 264.365
• InChiKey: SBBGIUSJPNPLJI-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  ethyl 4-[2-(3-hydroxybutyl)phenyl]butanoate 在 氢氧化钾 作用下， 以 1,4-二氧六环 为溶剂， 反应 16.0h， 以100%的产率得到4-[2-(3-hydroxybutyl)phenyl]butanoic acid
  参考文献：
  名称：

  Access to a new family of medium ring aromatic lactones

  摘要：

  We report a new method for preparation of hydroxyacids as precursors of benzolactones using a simple and an efficient electrochemical step. This gives in only four steps six- to eleven-membered lactones with high isolated yields from conveniently substituted aryl bromides. The lactonisation was performed according to the Yamamoto's process. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.06.071
• 作为产物：
  描述：

  ethyl 4-[2-(3-oxobutyl)phenyl]but-2-enoate 在 sodium tetrahydroborate 、 nickel dichloride 作用下， 以 甲醇 为溶剂， 反应 3.0h， 以100%的产率得到ethyl 4-[2-(3-hydroxybutyl)phenyl]butanoate
  参考文献：
  名称：

  Access to a new family of medium ring aromatic lactones

  摘要：

  We report a new method for preparation of hydroxyacids as precursors of benzolactones using a simple and an efficient electrochemical step. This gives in only four steps six- to eleven-membered lactones with high isolated yields from conveniently substituted aryl bromides. The lactonisation was performed according to the Yamamoto's process. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.06.071