2-nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-phenylphosphonic acid diethyl ester | 76699-54-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-phenylphosphonic acid diethyl ester
• 英文别名: 2-Nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)phenylphosphonic acid diethyl ester；1-(3-diethoxyphosphoryl-4-nitrophenoxy)-2-nitro-4-(trifluoromethyl)benzene
• CAS: 76699-54-2
• 化学式: C₁₇H₁₆F₃N₂O₈P
• 分子量: 464.292
• InChiKey: PAFIKZMDQYOOSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  31
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  136
• 氢给体数：
  0
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  2-nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-phenylphosphonic acid diethyl ester 在 盐酸 作用下， 以 乙醇 为溶剂， 反应 24.0h， 生成 2-nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-phenyl-phosphonic acid
  参考文献：
  名称：

  Maier, L.; Duerr, D.; Rempfler, H., Phosphorus and Sulfur and the Related Elements, 1987, vol. 32, p. 19 - 36

  摘要：

  DOI：
• 作为产物：
  描述：

  1,2-dinitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-benzene 、 亚磷酸三乙酯 以 甲苯 为溶剂， 反应 19.0h， 以51.3%的产率得到2-nitro-5-(2'-nitro-4'-trifluoromethylphenoxy)-phenylphosphonic acid diethyl ester
  参考文献：
  名称：

  Maier, L.; Duerr, D.; Rempfler, H., Phosphorus and Sulfur and the Related Elements, 1987, vol. 32, p. 19 - 36

  摘要：

  DOI：

文献信息

• 2-Substituted 5-phenoxyphenylphosphonic acid derivatives
  申请人：Ciba-Geigy Corporation

  公开号：US04322375A1

  公开（公告）日：1982-03-30

  The present invention relates to novel herbicidal and plant growth-inhibiting 2-substituted 5-phenoxyphenylphosphonic acid derivatives of the formula ##STR1## wherein each of R.sub.1 and R.sub.2 independently is hydroxyl, lower alkoxy, lower alkylthio, alkylamino, dialkylamino, chlorine, benzyloxy or benzylthio, X is halogen or a --CF.sub.3, --NO.sub.2, --CN, --CONH.sub.2 or --CSNH.sub.2 group, n is 0 to 3, and Y is --OH, halogen, NO.sub.2, --CN, NH.sub.2, --NHCO--R, --NHCOOR or --NH--SO.sub.2 --R, wherein R is an unsubstituted or halogenated lower alkyl radical. Preferred compounds are 2-nitro-5-(2'-chloro-4'-trifluoromethylphenoxy)-phenylphosphonic acid and the lower dialkyl esters thereof. The invention also relates to the production of the novel phosphonic acid derivatives, starting from a 3,4-dinitrodiphenyl ether and reacting it with a trialkylphosphite as first step. The invention further relates to herbicidal and plant growth-regulating compositions which contain one of the novel compounds as active component, and also to the use of these compounds and compositions for controlling weeds (also selectively), for inhibiting plant growth and desiccating parts of plants above the soil, as well as for totally destroying existing plant growth.

  本发明涉及新型除草和植物生长抑制剂2-取代的5-苯氧基苯基膦酸衍生物，其化学式为##STR1## 其中R.sub.1和R.sub.2各自独立地为羟基、低烷氧基、低烷基硫基、烷基氨基、二烷基氨基、氯、苄氧基或苄硫基，X为卤素或--CF.sub.3、--NO.sub.2、--CN、--CONH.sub.2或--CSNH.sub.2基团，n为0到3，Y为--OH、卤素、NO.sub.2、--CN、NH.sub.2、--NHCO--R、--NHCOOR或--NH--SO.sub.2--R，其中R为未取代或卤代的低烷基基团。首选化合物为2-硝基-5-(2'-氯-4'-三氟甲基苯氧基)-苯基膦酸及其较低的二烷基酯。本发明还涉及从3,4-二硝基二苯醚出发，并将其与三烷基膦酸酯反应作为第一步的新型膦酸衍生物的制备。本发明还涉及含有新型化合物作为活性成分的除草剂和植物生长调节剂组合物，以及使用这些化合物和组合物来控制杂草（也具有选择性）、抑制植物生长和脱水地上部分植物以及完全摧毁现有植物生长。
• Herbicidally active 2-substituted 5-phenoxyphenylphosphonic acid esters
  申请人：Ciba-Geigy Corporation

  公开号：US04391624A1

  公开（公告）日：1983-07-05

  The present invention relates to novel herbicidal and plant growth-inhibiting 2-substituted 5-phenoxyphenylphosphonic acid derivatives of the formula ##STR1## wherein each of R.sub.1 and R.sub.2 independently is hydroxyl, lower alkoxy, lower alkylthio, alkylamino, dialkylamino, chlorine, benzyloxy or benzylthio, X is halogen or a --CF.sub.3, --NO.sub.2, --CN, --CONH.sub.2 or --CSNH.sub.2 group, n is 0 to 3, and Y is --OH, halogen, NO.sub.2, --CN, NH.sub.2, --NHCO--R, --NHCOOR or --NH--SO.sub.2 --R, wherein R is an unsubstituted or halogenated lower alkyl radical. Preferred compounds are 2-nitro-5-(2'-chloro-4'-trifluoromethylphenoxy)-phenylphosphonic acid and the lower dialkyl esters thereof. The invention also relates to the production of the novel phosphonic acid derivatives, starting from a 3,4-dinitrodiphenyl ether and reacting it with a trialkylphosphite as first step. The invention further relates to herbicidal and plant growth-regulating compositions which contain one of the novel compounds as active component, and also to the use of these compounds and compositions for controlling weeds (also selectively), for inhibiting plant growth and desiccating parts of plants above the soil, as well as for totally destroying existing plant growth.

  本发明涉及一种新型的除草和抑制植物生长的2-取代的5-苯氧基苯基膦酸衍生物，其化学式为##STR1## 其中R.sub.1和R.sub.2各自独立地为羟基、低级烷氧基、低级烷基硫醚、烷基氨基、二烷基氨基、氯、苄氧基或苄硫醚，X为卤素或--CF.sub.3、--NO.sub.2、--CN、--CONH.sub.2或--CSNH.sub.2基团，n为0到3，Y为--OH、卤素、NO.sub.2、--CN、NH.sub.2、--NHCO--R、--NHCOOR或--NH--SO.sub.2--R，其中R为未取代或卤代的低级烷基基团。优选化合物为2-硝基-5-(2'-氯-4'-三氟甲基苯氧基)-苯基膦酸及其低级二烷酯。本发明还涉及从3,4-二硝基二苯醚开始，将其与三烷基膦酸酯反应作为第一步制备新型膦酸衍生物的方法。本发明还涉及含有新型化合物作为活性成分的除草和植物生长调节组合物，以及使用这些化合物和组合物来控制杂草（也具有选择性）、抑制植物生长和干燥地上部分植物，以及完全摧毁现有的植物生长。
• Herbicidally active 2-substituted 5-penoxyphenylphosphonic acid
  申请人：Ciba-Geigy Corporation

  公开号：US04421548A1

  公开（公告）日：1983-12-20

  The present invention relates to novel herbicidal and plant growth-inhibiting 2-substituted 5-phenoxyphenylphosphonic acid derivatives of the formula ##STR1## wherein each of R.sub.1 and R.sub.2 independently is hydroxyl, lower alkoxy, lower alkylthio, alkylamino, dialkylamino, chlorine, benzyloxy or benzylthio, X is halogen or a --CF.sub.3, --NO.sub.2, --CN, --CONH.sub.2 or --CSNH.sub.2 group, n is 0 to 3, and Y is --OH, halogen, NO.sub.2, --CN, NH.sub.2, --NHCO--R, --NHCOOR or --NH--SO.sub.2 --R, wherein R is an unsubstituted or halogenated lower alkyl radical. Preferred compounds are 2-nitro-5-(2'-chloro-4'-trifluoromethylphenoxy)-phenylphosphonic acid and the lower dialkyl esters thereof. The invention also relates to the production of the novel phosphonic acid derivatives, starting from a 3,4-dinitrodiphenyl ether and reacting it with a trialkylphosphite as first step. The invention further relates to herbicidal and plant growth-regulating compositions which contain one of the novel compounds as active component, and also to the use of these compounds and compositions for controlling weeds (also selectively), for inhibiting plant growth and desiccating parts of plants above the soil, as well as for totally destroying existing plant growth.

  本发明涉及一种新型除草和植物生长抑制剂，为式子##STR1##的2-取代5-苯氧基苯基膦酸衍生物，其中R.sub.1和R.sub.2各自独立地为羟基、低级烷氧基、低级烷基硫醇、烷基氨基、二烷基氨基、氯、苄氧基或苄基硫醇，X为卤素或--CF.sub.3、--NO.sub.2、--CN、--CONH.sub.2或--CSNH.sub.2基团，n为0至3，Y为--OH、卤素、NO.sub.2、--CN、NH.sub.2、--NHCO--R、--NHCOOR或--NH--SO.sub.2--R，其中R为未取代或卤代的低级烷基基团。优选的化合物为2-硝基-5-(2'-氯-4'-三氟甲基苯氧基)-苯基膦酸及其较低的二烷基酯。本发明还涉及从3,4-二硝基二苯醚开始，将其与三烷基膦酸酯反应作为第一步，生产新型膦酸衍生物的方法。本发明还涉及含有新型化合物作为活性成分的除草和植物生长调节组合物，以及利用这些化合物和组合物来控制杂草（也具有选择性），抑制植物生长并使土壤上方的植物部分干燥，以及完全消除现有的植物生长。
• US4322375A
  申请人：——

  公开号：US4322375A

  公开（公告）日：1982-03-30
• US4391624A
  申请人：——

  公开号：US4391624A

  公开（公告）日：1983-07-05