N-Methyl-N-butyryl-aminoacetonitril | 36801-51-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-Methyl-N-butyryl-aminoacetonitril
• 英文别名: N-(cyanomethyl)-N-methylbutanamide
• CAS: 36801-51-1
• 化学式: C₇H₁₂N₂O
• 分子量: 140.185
• InChiKey: CPWKVGXAMUOBKH-UHFFFAOYSA-N

物化性质

• 沸点：
  257.3±23.0 °C(Predicted)
• 密度：
  0.988±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  44.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• IMIDAZO[1,2-A]PYRIDINE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS
  申请人：MEI Pharma, Inc.

  公开号：EP1863811B1

  公开（公告）日：2014-03-12
• IMIDAZO[1,2-a]PYRIDINE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS
  申请人：MEI Pharma, Inc.

  公开号：US20150038703A1

  公开（公告）日：2015-02-05

  The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to imidazo[1,2-a]pyridine containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with enzymes having histone deacetylase activities (HDAC).
• SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：US20210017168A1

  公开（公告）日：2021-01-21

  Substituted Pyrazolo-pyridines as GluN2B receptor ligands. Such compounds may be used in GluN2B receptor modulation and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by GluN2B receptor activity.
• US8648092B2
  申请人：——

  公开号：US8648092B2

  公开（公告）日：2014-02-11
• US9266882B2
  申请人：——

  公开号：US9266882B2

  公开（公告）日：2016-02-23