sodium (2E)-4-methyl-2-[(1Z)-prop-1-enyl]pent-2-enoate | 712265-69-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: sodium (2E)-4-methyl-2-[(1Z)-prop-1-enyl]pent-2-enoate
• 英文别名: sodium;(E)-4-methyl-2-[(Z)-prop-1-enyl]pent-2-enoate
• CAS: 712265-69-5
• 化学式: C₉H₁₃O₂*Na
• 分子量: 176.191
• InChiKey: QIWZMSFXWDGFKA-NLAQHMENSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] VALPROIC ACID ANALOGUES AND PHARMACEUTICAL COMPOSITIONS THEREOF<br/>[FR] ANALOGUES DE L'ACIDE VALPROIQUE ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT
  申请人：UNIV BRITISH COLUMBIA

  公开号：WO2004054957A2

  公开（公告）日：2004-07-01

  Analogues of valproic acid useful in treating neuroaffective disorders including convulsions, bipolar disorder, and migraine headache are disclosed. The analogues are halide substituted analogues, cyclic analogues, and conjugated diene analogues of valproic acid. Pharmaceutical compositions or prodrugs containing the analogues or pharmaceutically acceptable salts thereof are disclosed. Methods of making the compounds and treating mammals with neuroaffective disorders are also disclosed.