methyl {[(2S)-3-[1-(methyl2-acetylaminoacetate-1H-indol-3-yl)]-2-(t-butoxycarbonylamino)propanoylamino]acetylamino}acetate | 1187388-44-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl {[(2S)-3-[1-(methyl2-acetylaminoacetate-1H-indol-3-yl)]-2-(t-butoxycarbonylamino)propanoylamino]acetylamino}acetate
• CAS: 1187388-44-8
• 化学式: C₂₆H₃₅N₅O₉
• 分子量: 561.592
• InChiKey: YSDYBTWIFHCAMA-SFHVURJKSA-N

反应信息

• 作为反应物：
  描述：

  methyl {[(2S)-3-[1-(methyl2-acetylaminoacetate-1H-indol-3-yl)]-2-(t-butoxycarbonylamino)propanoylamino]acetylamino}acetate 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以100%的产率得到methyl {(2S)-3-[1-(methyl2-acetylaminoacetate-1H-indol-3-yl)]-2-[(aminopropanoyl)amino]acetylamino}acetate
  参考文献：
  名称：

  Amino acid derivatives, X [1]: synthesis and antimicrobial evaluation of α-amino acid esters bearing a N1-protected tryptophan side chain

  摘要：

  A series of peptide derivatives conjugated with N-1-protected tryptophan residue was synthesized. The prepared compounds were tested for antimicrobial activity against four different bacterial species displaying different degrees of antibacterial activities or inhibitory actions.

  DOI：

  10.1007/s00706-008-0089-z
• 作为产物：
  描述：

  、 甘氨酸甲酯盐酸盐 在 三乙胺 作用下， 反应 24.0h， 生成 methyl {[(2S)-3-[1-(methyl2-acetylaminoacetate-1H-indol-3-yl)]-2-(t-butoxycarbonylamino)propanoylamino]acetylamino}acetate
  参考文献：
  名称：

  Amino acid derivatives, X [1]: synthesis and antimicrobial evaluation of α-amino acid esters bearing a N1-protected tryptophan side chain

  摘要：

  A series of peptide derivatives conjugated with N-1-protected tryptophan residue was synthesized. The prepared compounds were tested for antimicrobial activity against four different bacterial species displaying different degrees of antibacterial activities or inhibitory actions.

  DOI：

  10.1007/s00706-008-0089-z