3-[[(Acetylamino)methyl]thio]-D-valine | 300583-01-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-[[(Acetylamino)methyl]thio]-D-valine
• 英文别名: (2S)-3-(acetamidomethylsulfanyl)-2-amino-3-methylbutanoic acid
• CAS: 300583-01-1
• 化学式: C₈H₁₆N₂O₃S
• 分子量: 220.29
• InChiKey: GQQNNVPXBJJABF-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  118
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Acceleration of Mycobacterium growth
  申请人：ST GEORGE'S HOSPITAL MEDICAL SCHOOL

  公开号：US10633630B2

  公开（公告）日：2020-04-28

  The invention is in the field of growth of Mycobacteria. In particular, agents have been identified which enhance the growth of Mycobacterial species, which are naturally slow-growing. Such agents can therefore be used in the identification of Mycobacteria and in the diagnosis of Mycobacterial infections.

  本发明属于分枝杆菌生长领域。特别是，已经发现了能促进自然生长缓慢的分枝杆菌生长的制剂。因此，这些制剂可用于分枝杆菌的鉴定和分枝杆菌感染的诊断。
• SMALL CATIONIC ANTIMICROBIAL PEPTIDES
  申请人：THE UNIVERSITY OF BRITISH COLUMBIA

  公开号：EP2061886A1

  公开（公告）日：2009-05-27
• EP2061886B1
  申请人：——

  公开号：EP2061886B1

  公开（公告）日：2014-05-07
• ACCELERATION OF MYCOBACTERIUM GROWTH
  申请人：St. George's Hospital Medical School

  公开号：EP3158053A1

  公开（公告）日：2017-04-26
• Small Cationic Antimicrobial Peptides
  申请人：Hancock Robert E.

  公开号：US20110150917A1

  公开（公告）日：2011-06-23

  Cationic bacteriocin and lantibiotic peptides are provided and their immunomodulatory activities are described. Methods are provided for selectively enhancing innate immunity. Other methods are provided for selectively suppressing a proinflammatory response. Other methods are provided for identifying a compound or compounds which modulate an innate immune response. Pharmaceutical compositions comprising the cationic bacteriocin and lantibiotic peptides or polynucleotides are also provided.