(E)-Latanoprostene Bunod | 2099033-66-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-Latanoprostene Bunod
• 英文别名: 4-nitrooxybutyl (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
• CAS: 2099033-66-4
• 化学式: C27H41NO8
• 分子量: 507.6
• InChiKey: LOVMMUBRQUFEAH-LMDVOQDDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  36
• 可旋转键数：
  18
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  142
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• PROCESS FOR THE PREPARATION OF LATANOPROSTENE BUNOD AND INTERMEDIATE THEREOF AND COMPOSITIONS COMPRISING THE SAME
  申请人：CHIROGATE INTERNATIONAL INC.

  公开号：US20220024849A1

  公开（公告）日：2022-01-27

  Processes for preparing latanoprostene bunod and an intermediate prepared from the process. Also latanoprostene bunod compositions having high-purity latanoprostene bunod.

  制备拉坦前列素布诺酯和从该过程制备的中间体的方法。另外还有具有高纯度拉坦前列素布诺酯的拉坦前列素布诺酯组合物。
• Process for the preparation of latanoprostene bunod and intermediate thereof and compositions comprising the same
  申请人：CHIROGATE INTERNATIONAL INC.

  公开号：US11332433B2

  公开（公告）日：2022-05-17

  Processes for preparing latanoprostene bunod and an intermediate prepared from the process. Also latanoprostene bunod compositions having high-purity latanoprostene bunod.

  制备拉坦前列素布诺德的工艺和由该工艺制备的中间体。还有具有高纯度拉坦前列腺素布诺的拉坦前列腺素布诺组合物。