2-methylpyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone | 76660-13-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-methylpyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone
• 英文别名: 2-Methylpyrrolo[3,4-f]isoindole-1,3,5,7-tetrone
• CAS: 76660-13-4
• 化学式: C₁₁H₆N₂O₄
• 分子量: 230.18
• InChiKey: LQXWMQJSVQWICA-UHFFFAOYSA-N

物化性质

• 密度：
  1.636±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  83.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-methylpyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 、 mineral oil 为溶剂， 反应 27.5h， 生成
  参考文献：
  名称：

  [EN] METHANOGEN INHIBITORS
  [FR] INHIBITEURS DE MÉTHANOGÈNE

  摘要：

  The present invention relates to a new class of methanogen inhibitors for ruminants, in particular new pyromellitic diimide derivatives for ruminants. The invention also extends to the use of such derivatives in ruminants to reduce methane production in the rumen and/or to enhance productivity in the ruminant.

  公开号：

  WO2023048582A1
• 作为产物：
  描述：

  2,4,5-tricarboxybenzamide 在 氯化亚砜 作用下， 以 乙醇 、 丙酮 为溶剂， 反应 2.5h， 生成 2-methylpyrrolo[3,4-f]isoindole-1,3,5,7(2H,6H)-tetraone
  参考文献：
  名称：

  [EN] METHANOGEN INHIBITORS
  [FR] INHIBITEURS DE MÉTHANOGÈNE

  摘要：

  本发明涉及一种新的瘤胃甲烷生成菌抑制剂类别，特别是用于反刍动物的新的苯四酸二酰亚胺衍生物。本发明还涉及在反刍动物中使用此类衍生物以减少瘤胃中的甲烷产生和/或增强反刍动物生产力的方法。

  公开号：

  WO2022103280A1

文献信息

• Pyromellitic diimides, processes for their preparation, these compounds in orally administrable form for use in increasing the feed efficiency of a ruminant animal and compositions for this purpose containing them
  申请人：Merck & Co., Inc.

  公开号：EP0010440A1

  公开（公告）日：1980-04-30

  Asymmetrically substituted pyromellitic diimides of formula: in which R, and R2 are not the same and each represents hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, lower alkanoyl, benzoyl, di(lower alkyl)amino, lower alkanoylamino, benzoylamino, lower alkoxycarbonylamino or certain substituted phenyl or substituted lower alkyl radicals and each ofX and Y is hydrogen, halogen or lower alkyl, are novel compounds that are obtainable by treating pyromellitic dianhydride with two appropriately substituted amines or with ammonia and one amine. The compounds can be administered to ruminant animals to increase their feed efficiency and suitable compositions for this purpose include the compounds with an inert carrier.

  式中的不对称取代的吡咯烷二亚胺： 式中：R, 和 R2 不相同，各自代表氢、烷基、烯基、炔基、环烷基、低级烷酰基、苯甲酰基、二（低级烷基）氨基、低级烷酰基氨基、苯甲酰基氨基、低级烷氧基羰基氨基或某些取代苯基或取代低级烷基，X 和 Y 各自代表氢、卤素或低级烷基。 这些化合物可用于反刍动物，以提高其饲料效率，用于此目的的合适组合物包括带有惰性载体的化合物。
• RETARDATION FILM, NOVEL POLYMER, OPTICAL FILM AND IMAGE DISPLAY APPARATUS
  申请人：NITTO DENKO CORPORATION

  公开号：EP1772756A1

  公开（公告）日：2007-04-11

  A retardation film according to the present invention consists of a single-layer film in which a birefringent chain polymer is oriented, the polymer having as a repeating unit (A), a structure represented by the following general formula (V) : wherein R3 represents a hydrogen atom or an alkyl group having 1 to 8 carbon atoms; R4 and R8 each independently represent a hydrogen atom, a linear or branched alkyl group having 1 to 4 carbon atoms, a linear or branched alkoxyl group having 1 to 4 carbon atoms, a linear or branched thioalkoxyl group having 1 to 4 carbon atoms, halogen, a nitro group, an amino group, a hydroxyl group, or a thiol group (where R4 and R8 are not simultaneously hydrogen atoms); and R5, R6, and R7 each independently represent a hydrogen atom or a substituent. The retardation film can be relatively small in thickness and exhibits wavelength dispersion characteristics such that retardation for light having a wavelength of λ lying within almost the entire visible light wavelength range is about λ/2 or λ/4.

  根据本发明，一种缓凝薄膜由单层薄膜组成，在单层薄膜中定向使用双折射链聚合物，该聚合物的重复单元（A）具有以下通式（V）表示的结构： 其中 R3 代表氢原子或具有 1 至 8 个碳原子的烷基；R4 和 R8 各自独立地代表氢原子、具有 1 至 4 个碳原子的直链或支链烷基、具有 1 至 4 个碳原子的直链或支链烷氧基、具有 1 至 4 个碳原子的直链或支链硫代烷氧基、卤素、硝基、氨基、羟基或硫醇基（其中 R4 和 R8 不同时为氢原子）；以及 R5、R6 和 R7 各自独立地代表氢原子或取代基。 延缓膜的厚度可以相对较小，并具有波长分散特性，对于波长为 λ 的光，延缓率约为λ/2 或 λ/4，其波长几乎位于整个可见光波长范围内。
• Polyimide copolymer oligomer, polyimide copolymer, and method for producing each of same
  申请人：SOMAR CORPORATION

  公开号：US10246555B2

  公开（公告）日：2019-04-02

  Provided are: an oligomer of polyimide copolymer which is an intermediate of a polyimide copolymer having excellent utility and satisfying solvent solubility, storage stability and heat resistance at high levels; a polyimide copolymer obtained therefrom; and their production methods. The oligomer of polyimide copolymer and the polyimide copolymer are obtained by copolymerizing (A) 3,3′,4,4′-biphenyltetracarboxylic dianhydride and/or 3,3′,4,4′-diphenylsulfonetetracarboxylic dianhydride with (B) at least one diamine and/or diisocyanate represented by the following Formulae (1) to (3): (wherein, X represents an amino group or an isocyanate group; R1 to R8 each independently represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 2 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms; and at least one of the R1 to R8 is not a hydrogen atom).

  本文提供了：一种聚酰亚胺共聚物的低聚物，它是一种聚酰亚胺共聚物的中间体，具有优异的实用性，并能满足高水平的溶剂溶解性、储存稳定性和耐热性；由此获得的一种聚酰亚胺共聚物；以及它们的生产方法。聚酰亚胺共聚物的低聚物和聚酰亚胺共聚物是由(A)3,3′,4,4′-联苯四羧酸二酐和/或 3,3′,4,4′-二苯基磺酰四羧酸二酐与(B)至少一种由下式(1)至(3)代表的二胺和/或二异氰酸酯共聚而得： (其中，X 代表氨基或异氰酸酯基团；R1 至 R8 各自独立地代表氢原子、具有 1 至 4 个碳原子的烷基、具有 2 至 4 个碳原子的烯基或具有 1 至 4 个碳原子的烷氧基；且 R1 至 R8 中至少有一个不是氢原子）。
• Pyromellitic diimide complexes, their preparation, compositions containing them and their use in improving the feed efficiency of ruminants
  申请人：Merck & Co., Inc.

  公开号：EP0015083B1

  公开（公告）日：1982-12-29
• OXYGEN SCAVENGING ADDITIVES FOR PLASTIC CONTAINERS
  申请人：Graham Packaging Company, L.P.

  公开号：EP2566917B1

  公开（公告）日：2015-03-04