4-methoxy-4-phenylazo-2-methylpentan-2-ol | 1174301-64-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methoxy-4-phenylazo-2-methylpentan-2-ol
• CAS: 1174301-64-4
• 化学式: C₁₃H₂₀N₂O₂
• 分子量: 236.314
• InChiKey: GHWVMLKSUAKDIS-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  4-hydroxy-4-methyl-2-pentanone phenylhydrazone 、 sodium methylate 在 potassium iodide 作用下， 以 甲醇 为溶剂， 以77%的产率得到4-methoxy-4-phenylazo-2-methylpentan-2-ol
  参考文献：
  名称：

  Novel Application of an Electrooxidative Method for the Formation of a Tetrahydrofuran Ring from 5-Hydroxy-2-pentanone Phenylhydrazone

  摘要：

  Various ketone phenylhydrazones that possess a hydroxy group Oil the parent ketone moiety were subjected to electrooxidation in methanol ill the presence of KI and NaOMe. In the case of 4-hydroxy-2-butanone phenylhydrazone, the nucleophilic attack of the azomethine carbon by a methoxide ion affording the corresponding methoxy(phenylazo)alcohol was dominant. Interestingly, however, in the case of 5-hydroxy-2-pentanone phenylhydrazone, similar reaction conditions favored the intramolecular cyclization to afford a (phenylazo)tetrahydrofuran derivative.

  DOI：

  10.3987/com-09-11640