4-Ethyl-3-methyl-5-(3-methyl-6-oxo-cyclopentenopyrrolyl-(2)-methyl)-pyrrol-aldehyd-(2) | 22141-18-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 4-Ethyl-3-methyl-5-(3-methyl-6-oxo-cyclopentenopyrrolyl-(2)-methyl)-pyrrol-aldehyd-(2)
• 英文别名: 4-ethyl-3-methyl-5-(3-methyl-6-oxo-1,4,5,6-tetrahydro-cyclopenta[b]pyrrol-2-ylmethyl)-pyrrole-2-carbaldehyde；4-ethyl-3-methyl-5-[(3-methyl-6-oxo-4,5-dihydro-1H-cyclopenta[b]pyrrol-2-yl)methyl]-1H-pyrrole-2-carbaldehyde
• CAS: 22141-18-0
• 化学式: C₁₇H₂₀N₂O₂
• 分子量: 284.358
• InChiKey: OMQQATQOLSPPQY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  65.7
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS<br/>[FR] PROCÉDÉS DE FABRICATION DE MACROCYCLES BACTÉRIOCHLORINES COMPRENANT UN NOYAU ISOCYCLIQUE ANNELÉ ET DES COMPOSÉS APPARENTÉS
  申请人：UNIV NORTH CAROLINA STATE

  公开号：WO2018102252A1

  公开（公告）日：2018-06-07

  Described herein are bacteriochlorins comprising an annulated isocyclic ring. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).

  本文描述了包含环接合异环戊二烯环的细菌叶绿素。还描述了合成包含环接合异环戊二烯环的细菌叶绿素的方法和中间体，以及利用这种细菌叶绿素进行诊断和治疗等用途的方法，例如，在流式细胞术中用作发光化合物，和/或作为光动力疗法（PDT）中的活性剂。
• SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES
  申请人：Lindsey Jonathan S.

  公开号：US20090227553A1

  公开（公告）日：2009-09-10

  The present invention provides compounds of the general Formula DI: along with methods of making such compounds, formulations containing the same, and methods of using the same (e.g., in photodynamic therapy, for the production of solar cells, etc.)

  本发明提供了一般公式DI的化合物，以及制备此类化合物的方法，包含此类化合物的配方，以及使用此类化合物的方法（例如，用于光动力疗法，用于太阳能电池的生产等）。
• Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds
  申请人：North Carolina State University

  公开号：US10836774B2

  公开（公告）日：2020-11-17

  Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).

  本文描述的细菌氯化物包含一个环状异环，如式 I 化合物： 或其金属共轭物，其中R1、R2、R3、R4、R5、R6、R7、R8、R9、R10、R11、R12、R13、R14、R15、R16 和 Z 均如本文所定义。还描述了合成包含环状异环的细菌氯化物的方法和中间体，以及将这种细菌氯化物用于诊断和治疗目的的方法，例如流式细胞术中的发光化合物和/或作为光动力疗法（PDT）中的活性剂。
• METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS
  申请人：North Carolina State University

  公开号：US20190308985A1

  公开（公告）日：2019-10-10

  Described herein are bacteriochlorins comprising an annulated isocyclic ring. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).
• US8207329B2
  申请人：——

  公开号：US8207329B2

  公开（公告）日：2012-06-26