4,5,6,7-四氟-2-甲基-1,3-苯并噻唑 | 70016-00-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 中文名称: 4,5,6,7-四氟-2-甲基-1,3-苯并噻唑
• 英文名称: 2-methyl-4,5,6,7-tetrafluorobenzothiazole
• 英文别名: 4,5,6,7-tetrafluoro-2-methylbenzothiazole；4,5,6,7-tetrafluoro-2-methyl-benzothiazole；2-Methyl-4,5,6,7-tetrafluorbenzothiazol；4,5,6,7-Tetrafluoro-2-methyl-1,3-benzothiazole
• CAS: 70016-00-1
• 化学式: C₈H₃F₄NS
• 分子量: 221.178
• InChiKey: MDVWTPBRQGXJRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  41.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4,5,6,7-四氟-2-甲基-1,3-苯并噻唑 在 吡啶 、 硫酸二乙酯 作用下， 反应 26.5h， 生成 3,3'-diethyl-4,4',5,5',6,6',7,7'-octafluorothiadicarbocyanine ethyl sulfate
  参考文献：
  名称：

  Improved Photostability and Fluorescence Properties through Polyfluorination of a Cyanine Dye

  摘要：

  A polyfluorinated cyanine dye has been synthesized and characterized. Compared with the nonfluorinated analogue, the dye exhibits significantly reduced aggregation in aqueous media, enhanced fluorescence quantum yield, greater resistance to photobleaching upon direct irradiation, and reduced reactivity toward singlet oxygen. All of these properties are favorable for use of cyanine dyes as fluorescent labels and point toward fluorination as a general strategy for improving performance in imaging applications.

  DOI：

  10.1021/ol036081w

文献信息

• Two-part cyanoacrylate curable adhesive system
  申请人：Henkel IP & Holding GmbH

  公开号：US10100235B2

  公开（公告）日：2018-10-16

  Two-part cyanoacrylate compositions, methods for making same, and uses therefor are described. The compositions can be used to bond a variety of substrates including plastics and metals. The compositions remain effective after thermal ageing and humid ageing.

  描述了双组分氰基丙烯酸酯组合物、其制造方法及其用途。这些组合物可用于粘合各种基材，包括塑料和金属。这种组合物在经过热老化和湿老化后仍然有效。
• Luminescent Zinc(II) Complexes of Fluorinated Benzothiazol-2-yl Substituted Phenoxide and Enolate Ligands
  作者：Zhe Li、Ahmed Dellali、Jahangir Malik、Majid Motevalli、Roger M. Nix、Toyin Olukoya、Yu Peng、Huanqing Ye、William P. Gillin、Ignacio Hernández、Peter B. Wyatt

  DOI：10.1021/ic302063u

  日期：2013.2.4

  Zn(II) complexes of the following new, fluorine-containing, benzothiazole-derived ligands have been synthesized and characterized crystallographically: 2-(3,3,3-trifluoro-2oxopropyl)benzothiazole (3), 4,5,6,7-tetrafluoro-2-(3,3,3-trifluoro-2-oxopropyl)benzothiazole (4), 4,5,6,7-tetrafluoro-2-(2hydroxyphenyl)benzothiazole (12), 2-(3,4,5,6-tetrafluoro-2-hydroxypheny1)-4,5,6,7-tetrafluorobenzothiazole (13), and 2(3,4,5,6-tetrafluoro-2-hydroxyphenyObenzothiazole (16); the Cu(II) complex of ligand 4 is also reported. These are analogs of the important photo- and electroluminescent material [Zn(BTZ)(2)](2), where H-BTZ = 2-(2-hydroxyphenyObenzothiazole. DFT calculations indicate that HOMO and LUMO energy levels in these materials are substantially lowered by fluorination. The fluorinated ZnL2 complexes are mononuclear (in contrast to the dinudear, nonfluorinated material [Zn(BTZ)(2)](2)). They easily sublime and show broad visible photoluminescence. A common crystallographic feature is the existence of pairs of fluorinated ZnL2 molecules related by inversion centers, with their pi systems facing one another.
• TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM
  申请人：Henkel IP & Holding GmbH

  公开号：EP3464446A1

  公开（公告）日：2019-04-10
• ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES
  申请人：Hally William

  公开号：US20110196092A1

  公开（公告）日：2011-08-11

  There is provided a cyanoacrylate composition comprising: a cyanoacrylate; and a 2-substituted benzothiazole or a derivative thereof wherein the 2-substituent is an alkyl, an alkene, an alkylbenzyl, an alkylamino, an alkoxy, an alkylhydroxy, an ether, a sulfenamide, a thioalkyl or a thioalkoxy group, with the proviso that an amide portion of the sulfenamide does not have a tert butylamino or a morpholine group.
• US8933168B2
  申请人：——

  公开号：US8933168B2

  公开（公告）日：2015-01-13