N-(2-(methyl(tetradecyl)amino)acetyl)-N-methyl-D-glucamine hydrotrifluoroacetate | 1415035-36-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(2-(methyl(tetradecyl)amino)acetyl)-N-methyl-D-glucamine hydrotrifluoroacetate
• 英文别名: N-methyl-2-[methyl(tetradecyl)amino]-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]acetamide;2,2,2-trifluoroacetic acid
• CAS: 1415035-36-7
• 化学式: C₂HF₃O₂*C₂₄H₅₀N₂O₆
• 分子量: 576.695
• InChiKey: FNMYVVDJVKNHKJ-YWQMVABISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.15
• 重原子数：
  39
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  162
• 氢给体数：
  6
• 氢受体数：
  12

文献信息

• [EN] HYDROXY-SUBSTITUTED AMINO AND AMMONIUM DERIVATIVES AND THEIR MEDICAL USE<br/>[FR] DÉRIVÉS AMINO ET AMMONIUM À SUBSTITUTION HYDROXY ET LEUR UTILISATION MÉDICALE
  申请人：JADO TECHNOLOGIES GMBH

  公开号：WO2012160188A1

  公开（公告）日：2012-11-29

  The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.

  本发明涉及羟基取代的氨基和铵衍生物，特别是式（1）或（2）的化合物，以及它们的医疗用途，包括在治疗、预防或改善炎症性、自身免疫和/或过敏性疾病，或增生性、肿瘤性或异型增生性疾病或紊乱中的应用。
• HYDROXY-SUBSTITUTED AMINO AND AMMONIUM DERIVATIVES AND THEIR MEDICAL USE
  申请人：Schlechtingen Georg

  公开号：US20150232418A1

  公开（公告）日：2015-08-20

  The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.

  本发明涉及羟基取代的氨基和铵衍生物，特别是公式（1）或（2）化合物及其医学用途，包括用于治疗、预防或改善炎症、自身免疫和/或过敏性疾病，或增殖性、肿瘤性或畸形性疾病或障碍。
• Hydroxy-substituted amino and ammonium derivatives and their medical use
  申请人：GRI BIO, INC.

  公开号：US10143668B2

  公开（公告）日：2018-12-04

  The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.

  本发明涉及羟基取代的氨基和铵衍生物，特别是式 (1) 或 (2) 的化合物及其医疗用途，包括用于治疗、预防或改善炎症、自身免疫和/或过敏性疾病，或增生性、肿瘤性或发育不良性疾病或紊乱。
• US9573886B2
  申请人：——

  公开号：US9573886B2

  公开（公告）日：2017-02-21