2-Methylaminomethyl-acrylsaeureethylester | 27316-05-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Methylaminomethyl-acrylsaeureethylester
• 英文别名: 2-Methylaminomethyl-acrylsaeureaethylester；Ethyl 2-(methylaminomethyl)prop-2-enoate
• CAS: 27316-05-8
• 化学式: C₇H₁₃NO₂
• 分子量: 143.186
• InChiKey: SBWGHIDEZQKFSC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] DIAZEPINONE DERIVATIVES AS CAPSID ASSEMBLY MODULATORS<br/>[FR] DÉRIVÉS DE DIAZÉPINONE UTILISÉS COMME MODULATEURS D'ASSEMBLAGE DE CAPSIDE
  申请人：JANSSEN SCIENCES IRELAND UNLIMITED CO

  公开号：WO2020239863A1

  公开（公告）日：2020-12-03

  Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the HBV CAM. Such compounds are represented by Formula (I) as follows, wherein R1, R2, R3, X, and R4, are defined herein.

  揭示了一种用于治疗受HBV CAM影响的疾病、综合症、症状和疾病的化合物、组合物和方法。这些化合物由以下的化学式（I）表示，其中R1、R2、R3、X和R4在此处有定义。
• DIAZEPINONE DERIVATIVES AS CAPSID ASSEMBLY MODULATORS
  申请人：Janssen Sciences Ireland Unlimited Company

  公开号：US20220213102A1

  公开（公告）日：2022-07-07

  Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the HBV CAM. Such compounds are represented by Formula (I) as follows: wherein R 1 , R 2 , R 3 , X, and R 4 , are defined herein.
• [EN] FUSED HETEROCYCLIC DERIVATIVES<br/>[FR] DÉRIVÉS HÉTÉROCYCLIQUES FUSIONNÉS
  申请人：JANSSEN SCIENCES IRELAND UNLIMITED CO

  公开号：WO2020243135A1

  公开（公告）日：2020-12-03

  The application describes fused heterocycle derivative compounds, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases associated with HBV infection.