(Z)-7-{(1S,2S,3S,5R)-2-[(E)-(R)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-3,5-dihydroxy-cyclopentyl}-hept-5-enoic acid benzyl ester | 147555-72-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-7-{(1S,2S,3S,5R)-2-[(E)-(R)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-3,5-dihydroxy-cyclopentyl}-hept-5-enoic acid benzyl ester
• CAS: 147555-72-4
• 化学式: C₃₃H₅₄O₅Si
• 分子量: 558.874
• InChiKey: ZRUOACAIJOHLGR-HQIBNEGLSA-N

反应信息

• 作为反应物：
  描述：

  三光气 、 (Z)-7-{(1S,2S,3S,5R)-2-[(E)-(R)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-3,5-dihydroxy-cyclopentyl}-hept-5-enoic acid benzyl ester 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 以94%的产率得到(Z)-7-{(1S,5R,6S,7S)-7-[(E)-(R)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-3-oxo-2,4-dioxa-bicyclo[3.2.1]oct-6-yl}-hept-5-enoic acid benzyl ester
  参考文献：
  名称：

  A safe and efficient method for conversion of 1,2- and 1,3-diols to cyclic carbonates utilizing triphosgene

  摘要：

  Reaction of triphosgene in the presence of pyridine with a variety of diols including hindered tertiary and 1,3-cyclic diols provided high yields of the corresponding cyclic carbonates.

  DOI：

  10.1016/0040-4039(93)85085-b