4-(6-Methylbenzofuran-2-yl)benzonitril | 53390-11-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 2-芳基苯并呋喃类黄酮
• 英文名称: 4-(6-Methylbenzofuran-2-yl)benzonitril
• 英文别名: 6-Methylbenzofuran-2-yl-4-benzonitril
• CAS: 53390-11-7
• 化学式: C₁₆H₁₁NO
• 分子量: 233.269
• InChiKey: WDKTVQOZLLOTLC-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  (E)-N-(4-Chlorophenyl)-2-(4-cyanobenzyloxy)-4-methylbenzaldimin 在 sodium methylate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以88%的产率得到4-(6-Methylbenzofuran-2-yl)benzonitril
  参考文献：
  名称：

  Synthese von 2-alkoxysubstituierten Oligo- und Poly(1,4-phenylenethenylen)en und 2-Arylbenzo[b]furanen mit Hilfe der Siegrist-Reaktion

  摘要：

  Alkylation of 2-hydroxy-4-methylbenzaldehyde (1) yields the 2-alkoxy-4-methylbenzaldehydes (2a-1) which can be easily transformed to the Schiff bases 3a-1. The intermolecular self-condensation in a strongly alkaline medium leads to the oligo- and poly(1,4-phenyleneethenylene)s (4a-i) with an outstanding regular constitution and overall (E)-configuration. The terminal N-arylamino group can be cleaved by hydrolysis generating the compounds 5a-i. An intramolecular condensation forming the benzo[b]furanes 6j,k is observed for 3j,k - due to the activated OCH2 group in 2-position. Finally, both the 4-CH3 as well as the 2-OCH2 group take part in the reaction of 31. The twofold Schiff base 3m. obtained from 1 via 2m, yields the ladder polymer 7m.

  DOI：

  10.1002/prac.19943360205