2-azidoethyl N-tert-butylcarbamate | 1206487-54-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-azidoethyl N-tert-butylcarbamate
• CAS: 1206487-54-8
• 化学式: C₇H₁₄N₄O₂
• 分子量: 186.214
• InChiKey: XSUUEWBRSRRCFB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  52.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• SYNTHESIS PROCESS OF PRECURSORS OF DERIVATIVES OF BETA-LACTAM NUCLEI AND PRECURSORS AND DERIVATIVES THEREOF
  申请人：BONOMI Paolo

  公开号：US20180362544A1

  公开（公告）日：2018-12-20

  A synthesis process of precursors of derivatives of beta-lactam compounds, said beta-lactam compounds being selected from 6-aminopenicillanic acid and 7-aminocephalosporanic acid, preferably 6-aminopenicillanic acid, comprising the following steps: a) protection of the amine group of the beta-lactam compound, selected from 6-aminopenicillanic acid and 7-aminocephalosporanic acid, preferably 6-aminopenicillanic acid, through the formation of a carbamate by reaction with a dicarbonate; b) esterification of the carboxyl group in position 2 of the beta-lactam compound obtained in step a) by reaction with propargyl alcohol.