Darobactin A | 2409072-20-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Darobactin A
• 英文别名: (2S)-2-[[(2S)-2-[[(5R,17S,20S,23S,26S,29S,30S)-17-amino-20-(2-amino-2-oxoethyl)-30-(3-aminopropyl)-26-(hydroxymethyl)-18,21,24,27-tetraoxo-6-oxa-2,13,19,22,25,28-hexazahexacyclo[29.3.1.04,34.05,23.07,12.011,15]pentatriaconta-1(34),3,7,9,11,14,31(35),32-octaene-29-carbonyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoic acid
• CAS: 2409072-20-2
• 化学式: C₄₇H₅₅N₁₁O₁₂
• 分子量: 966.0
• InChiKey: HRMCRRLPTVSYHJ-KUDSBEMESA-N

文献信息

• Isolated darobactin A analog compounds and compositions thereof
  申请人：Northeastern University

  公开号：US11535648B2

  公开（公告）日：2022-12-27

  Embodiments of the present invention relate to a novel compound of Formula (I) or stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, for use in treatment of infection caused by Gram-negative bacteria.

  本发明的实施方案涉及一种新型的式(I)化合物或立体异构体、同分异构体或其药学上可接受的盐，用于治疗革兰氏阴性菌引起的感染。