(+/-)-2-Amino-4-hexylmercapto-buttersaeure | 23513-69-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (+/-)-2-Amino-4-hexylmercapto-buttersaeure
• 英文别名: 2-Amino-4-hexylsulfanylbutanoic acid
• CAS: 23513-69-1
• 化学式: C₁₀H₂₁NO₂S
• 分子量: 219.348
• InChiKey: ANMGALVEODQZHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  88.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USES FOR BOTH
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP3168302A1

  公开（公告）日：2017-05-17

  A polynucleotide encoding an amino acid sequence represented by SEQ ID NO: 1 or 3; a protein having an amino acid sequence represented by SEQ ID NO: 1 or 3; and; a method for producing an L-α-amino acid compound, which comprises the step (1) for reacting the present invented protein with an α-hydroxycarboxylic acid compound to obtain a corresponding α-oxocarboxylic acid compound, and the step of reacting a protein having the ability to aminate an α-oxocarboxylic acid compound and convert the same into a corresponding L-α-amino acid compound with the α-oxocarboxylic acid compound obtained in the step (1) to obtain a corresponding L-α-amino acid compound; and the like.

  编码由 SEQ ID NO: 1 或 3 所代表的氨基酸序列的多核苷酸；具有由 SEQ ID NO：1或3所代表的氨基酸序列的蛋白质；以及一种生产 L-α-氨基酸化合物的方法，该方法包括步骤(1)，将本发明的蛋白质与 α-羟基羧酸化合物反应，得到相应的 α-氧代羧酸化合物、以及将具有氨化α-氧羧酸化合物并将其转化为相应的 L-α-氨基酸化合物的能力的蛋白质与步骤（1）中获得的α-氧羧酸化合物反应，以获得相应的 L-α-氨基酸化合物的步骤；等。
• Oxidase, polynucleotide that codes for same, and use thereof
  申请人：Sumitomo Chemical Company

  公开号：US10351829B2

  公开（公告）日：2019-07-16

  A polynucleotide encoding an amino acid sequence represented by SEQ ID NO: 1 or 3; a protein having an amino acid sequence represented by SEQ ID NO: 1 or 3; and a method for producing an L-α-amino acid compound are provided. The method includes a step (1) of reacting the protein described herein with an α-hydroxycarboxylic acid compound to obtain a corresponding α-oxocarboxylic acid compound; and a step of reacting a protein having the ability to aminate an α-oxocarboxylic acid compound and convert the same into a corresponding L-α-amino acid compound with the α-oxocarboxylic acid compound obtained in step (1) to obtain a corresponding L-α-amino acid compound.

  本发明提供了一种编码由 SEQ ID NO: 1 或 3 所代表的氨基酸序列的多核苷酸；一种具有由 SEQ ID NO: 1 或 3 所代表的氨基酸序列的蛋白质；以及一种生产 L-α-氨基酸化合物的方法。该方法包括步骤(1)，将本文所述的蛋白质与α-羟基羧酸化合物反应，得到相应的α-氧代羧酸化合物；以及步骤(2)，将具有氨化α-氧代羧酸化合物并将其转化为相应的L-α-氨基酸化合物的能力的蛋白质与步骤(1)中得到的α-氧代羧酸化合物反应，得到相应的L-α-氨基酸化合物。
• Method for producing L-α-amino acid compound
  申请人：Sumitomo Chemical Company, Limited

  公开号：US10364448B2

  公开（公告）日：2019-07-30

  Isolated oxidases, isolated polynucleotides encoding the oxidases, and methods of using the oxidases to produce α-oxocarboxylic acid compounds or L-α-amino acid compounds are described.

  本文描述了分离的氧化酶、编码氧化酶的分离多核苷酸以及使用氧化酶生产α-氧代羧酸化合物或L-α-氨基酸化合物的方法。
• OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE OF THESE
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP3168301B1

  公开（公告）日：2019-11-20
• OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USE THEREOF
  申请人：Sumitomo Chemical Company, Limited

  公开号：US20170159029A1

  公开（公告）日：2017-06-08

  A polynucleotide encoding an amino acid sequence represented by SEQ ID NO: 1 or 3; a protein having an amino acid sequence represented by SEQ ID NO: 1 or 3; and a method for producing an L-α-amino acid compound are provided. The method includes a step (1) of reacting the protein described herein with an α-hydroxycarboxylic acid compound to obtain a corresponding α-oxocarboxylic acid compound; and a step of reacting a protein having the ability to aminate an α-oxocarboxylic acid compound and convert the same into a corresponding L-α-amino acid compound with the α-oxocarboxylic acid compound obtained in step (1) to obtain a corresponding L-α-amino acid compound.