[EN] A METHOD OF MODULATING PROTEIN 14-3-3 FUNCTIONALITY BY FACILITATING OR INHIBITING PHOSPHORYLATION<br/>[FR] PROCÉDÉ DE MODULATION DE LA FONCTIONNALITÉ DE LA PROTÉINE 14-3-3 PAR ACTIVATION OU INHIBITION DE LA PHOSPHORYLATION
申请人:MEDVET SCIENCE PTY LTD
公开号:WO2011120082A1
公开(公告)日:2011-10-06
The present invention relates to a method of modulating cellular activity. More particularly, the present invention provides a method of modulating apoptosis by modulating protein 14-3-3 phosphorylation and, thereby, its functionality. The present invention still further extends to methods for identifying agents capable of modulating protein 14-3-3 phosphorylation. The method and molecules of the present invention are useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by unwanted cellular activity, such as unwanted cell survival.