申请人:Thormar Halldor
公开号:US20050043402A1
公开(公告)日:2005-02-24
The present invention relates to a method for preventing infection of the genital mucosa of a mammal by virus, pathogenic bacteria or fungi, comprising topically administering, to the genital mucosa of the mammal, an effective prophylactic amount of a formulation comprising a hydrogel which comprises a microbicidal lipid as an active ingredient, a water gelling agent and a solubilizing agent. The microbicidal lipid is preferably a C6-18 fatty acid or salt thereof, fatty acid monoglycerides, fatty acid esters of monohydric alcohols, fatty alcohols or fatty alcohol monoglycerides ether.
本发明涉及一种预防哺乳动物生殖器粘膜受病毒、致病菌或真菌感染的方法,包括向哺乳动物的生殖器粘膜局部施用有效预防量的制剂,该制剂由水凝胶组成,水凝胶包括作为活性成分的杀微生物脂质、水胶凝剂和增溶剂。杀微生物脂质最好是 C6-18 脂肪酸或其盐、脂肪酸单甘酯、一元醇脂肪酸酯、脂肪醇或脂肪醇单甘酯醚。