3-[methyl-(4-nitro-1-oxypyridin-2-yl)amino]propan-1-ol | 643744-21-2

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: 3-[methyl-(4-nitro-1-oxypyridin-2-yl)amino]propan-1-ol
• 英文别名: 3-[Methyl-(4-nitro-1-oxidopyridin-1-ium-2-yl)amino]propan-1-ol
• CAS: 643744-21-2
• 化学式: C₉H₁₃N₃O₄
• 分子量: 227.22
• InChiKey: WYKQEVGSFJJBOP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  94.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] NOVEL METHOD & COMPOUNDS<br/>[FR] NOUVEAU PROCEDE ET COMPOSES ASSOCIES
  申请人：GLAXOSMITHKLINE SPA

  公开号：WO2004004715A2

  公开（公告）日：2004-01-15

  A method for the modulation of conditions associated with the delta opioid receptor, which method comprises the administration to the mammal in need thereof an effective or prophylactic amount of a compound of formula (I): wherein X, Y, Z, R1, and R2 are as defined in the specification; to compounds for use in such a method, to processes for their preparation, and to their use in medicine.