Icosa-5,8,11,14-tetraenoic anhydride | 55726-28-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Icosa-5,8,11,14-tetraenoic anhydride
• 英文别名: icosa-5,8,11,14-tetraenoyl icosa-5,8,11,14-tetraenoate
• CAS: 55726-28-8
• 化学式: C₄₀H₆₂O₃
• 分子量: 590.9
• InChiKey: FFBZPQRGHCBZJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.9
• 重原子数：
  43
• 可旋转键数：
  30
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• PREPARATION OF AMINO ACID-FATTY ACID ANHYDRIDES
  申请人：MacDougall Joseph

  公开号：US20080200725A1

  公开（公告）日：2008-08-21

  The present invention describes compounds produced from an amino acid molecule and a fatty acid molecule. The compounds being in the form of amino-fatty acid compounds being bound by an anhydride linkage, or mixtures thereof made by reacting amino acids or derivatives thereof with an appropriate fatty acid previously reacted with a thionyl halide. The administration of such molecules provides supplemental amino acids with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.

  本发明描述了由氨基酸分子和脂肪酸分子产生的化合物。这些化合物采用酐键连接的氨基-脂肪酸化合物形式存在，或者是由氨基酸或其衍生物与预先经过硫酰卤化物反应的适当脂肪酸混合物制成的。这些分子的使用提供了增强生物利用度的补充氨基酸以及特定脂肪酸所赋予的附加益处。
• Preparation of amino acid-fatty acid anhydrides
  申请人：MacDougall Joseph

  公开号：US20080281113A1

  公开（公告）日：2008-11-13

  The present invention describes compounds produced from an amino acid molecule and a fatty acid molecule. The compounds being in the form of amino-fatty acid compounds being bound by an anhydride linkage, or mixtures thereof made by reacting amino acids or derivatives thereof with an appropriate fatty acid previously reacted with a thionyl halide. The administration of such molecules provides supplemental amino acids with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.

  本发明描述了由氨基酸分子和脂肪酸分子产生的化合物。这些化合物采用酐键连接，形成氨基脂肪酸化合物，或者由氨基酸或其衍生物与事先与硫酰卤反应的适当脂肪酸混合而成。这些分子的使用提供了增强生物利用度的补充氨基酸和特定脂肪酸所赋予的额外益处。
• STRUCTURED PHOSPHOLIPIDS FOR TREATING AUTOIMMUNE AND NEURODEGENERATIVE DISEASES
  申请人：BTG INTERNATIONAL LIMITED

  公开号：EP1885377A2

  公开（公告）日：2008-02-13
• Structured Phospholipids
  申请人：Harbige Laurence S.

  公开号：US20090036410A1

  公开（公告）日：2009-02-05

  A method of treating a patient in need of therapy for a disease in which cyokines have become dysregulated, or are otherwise capable of modulation to provide therapeutic benefit, is provided comprising administering to that patient a therapeutically effective dose of a phospholipid comprising a phosphatidyl group esterifed with one or more fatty acyl groups, characterised in that the phospholipid has at least one fatty acyl group at the sn-1 and/or sn-2 position of the phosphatidyl group, the fatty acyl group being selected from the group consisting of γ-linolenoyl, dihomo-γ-linolenoyl acid and arachidonoyl.
• US4086417A
  申请人：——

  公开号：US4086417A

  公开（公告）日：1978-04-25