N-Nonylcarbaminsaeure | 63442-92-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-Nonylcarbaminsaeure
• 英文别名: nonyl-carbamic acid；Nonyl-carbamidsaeure；Kohlensaeure-mono-nonylamid；Azaundecanoic acid；nonylcarbamic acid
• CAS: 63442-92-2
• 化学式: C₁₀H₂₁NO₂
• 分子量: 187.282
• InChiKey: ZGSBJRRASOQRIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] TETRAZOLE AND OXADIAZOLONE SUBSTITUTED beta-AMINO ACID DERIVATIVES<br/>[FR] DERIVES DE beta-AMINOACIDES SUBSTITUES PAR TETRAZOLE ET OXADIAZOLONE
  申请人：WARNER LAMBERT CO

  公开号：WO2004078734A1

  公开（公告）日：2004-09-16

  This invention relates to novel tetrazole and oxadiazalone β-amino acids derivatives of the formula (I, II), wherein G is (III, IV) wherein R1 through R4 are defined as in the specification, pharmaceutical compositions containing them and their use for the treatment of various central nervous system and other disorders. The cyclopropyl β-amino acids derivatives of this invention exhibit activity as alpha2delta ligands (α2δ ligands). Such compounds have affinity for the α2δ subunit of a calcium channel.

  这项发明涉及公式(I, II)的新型四唑和氧代噁唑酮β-氨基酸衍生物，其中G为(III, IV)，其中R1至R4如规范中所定义，含有它们的药物组合物以及它们用于治疗各种中枢神经系统和其他疾病的用途。本发明的环丙基β-氨基酸衍生物表现出作为α2δ配体（α2δ配体）的活性。这类化合物对钙通道的α2δ亚基具有亲和力。
• ALKYL-, ALKENYL- AND ALKYNYLCARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
  申请人：ALMARIO-GARCIA Antonio

  公开号：US20080103197A1

  公开（公告）日：2008-05-01

  The invention relates to a compound of formula (I): Wherein R 1 , R 2 , R 3 and R 4 are as defined herein. The invention also relates to methods of preparation of compounds of formula (I) as well as to their therapeutic application.

  本发明涉及化合物(I)的公式，其中R1、R2、R3和R4如本文所定义。本发明还涉及制备化合物(I)的方法以及它们的治疗应用。
• Galanthamine derivatives, a process for their preparation and their use as medicaments
  申请人：HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED

  公开号：EP0648771A1

  公开（公告）日：1995-04-19

  This application relates to compounds of the formula wherein R¹, R² and R³ are defined within, which compounds are useful for the treatment of memory dysfunction characterized by decreased cholinergic function, pharmaceutical compositions containing the compounds and methods for making and using the compounds.

  本申请涉及式如下的化合物 其中 R¹、R² 和 R³ 的定义，该化合物可用于治疗以胆碱能功能减退为特征的记忆功能障碍、含有该化合物的药物组合物以及制造和使用该化合物的方法。
• Detergent composition
  申请人：Reckitt Benckiser N.V.

  公开号：US10066192B2

  公开（公告）日：2018-09-04

  A detergent composition comprising a subtilisin variant having the amino acid sequence set forth in SEQ ID NO: 1, and at least one additional ingredient selected from i) bleaches selected from percarbonates, persulphates and organic peracids, ii) aminocarboxylates, or iii) sulphonated polymers, or iv) organophosphoric acids or salts thereof and mixtures thereof is provided. Also provided is a detergent composition comprising a subtilisin variant having the amino acid sequence set forth in SEQ ID NO: 1, wherein the detergent composition is at least partially enveloped in a water soluble or water dispersible package. The compositions exhibit good performance on proteinaceous stains, even when formulated at alkaline pHs. A method of removing proteinaceous stains from surfaces comprising such stains is also provided.

  本发明提供了一种洗涤剂组合物，该组合物包含具有 SEQ ID NO: 1 所列氨基酸序列的枯草毒素变体，以及至少一种额外成分，这些成分选自 i) 选自过碳酸盐、过硫酸盐和有机过酸的漂白剂，ii) 氨基羧酸盐，或 iii) 磺化聚合物，或 iv) 有机磷酸或其盐及其混合物。还提供了一种洗涤剂组合物，该组合物包含具有 SEQ ID NO: 1 所列氨基酸序列的枯草蛋白变体，其中洗涤剂组合物至少部分包裹在水溶性或水分散性包装中。即使在碱性 pH 值下配制，这些组合物对蛋白藻类污渍也有良好的去污效果。此外，还提供了一种从包含此类污渍的表面去除蛋白质污渍的方法。
• METHOD OF PRODUCING ORGANIC DIURETHANES AND/OR POLYURETHANES AND THEIR USE IN THE PRODUCTION OF DI-AND/OR POLYISOCYANATES
  申请人：——

  公开号：US20010005761A1

  公开（公告）日：2001-06-28

  Organic diurethanes and/or polyurethanes are prepared by reacting organic diamines and/or polyamines (a) with urea and/or alkyl cabamates (b) and alcohols (c) in the presence of soluble zirconium compounds, preferably zirconium alkoxides, zirconium acetate or zirconium acetylacetonate, as catalyst (d). They can be used for preparing diisocyanates and/or polyisocyanates by thermal dissociation.

  有机二胺和/或多胺（a）与脲和/或烷基卡巴梅酸酯（b）和醇（c）在可溶性锆化合物，最好是烷氧基锆、乙酸锆或乙酰丙酮酸锆作为催化剂（d）的存在下反应，可制备有机二氨基甲酸酯和/或聚氨酯。它们可用于通过热解离制备二异氰酸酯和/或多异氰酸酯。