2-aminomethyl-3-hydroxy-pyran-4-one | 73114-99-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: 2-aminomethyl-3-hydroxy-pyran-4-one
• 英文别名: 2-(aminomethyl)-3-hydroxy-4H-pyran-4-one；2-(aminomethyl)-3-hydroxypyran-4-one
• CAS: 73114-99-5
• 化学式: C₆H₇NO₃
• mdl: MFCD19208758
• 分子量: 141.126
• InChiKey: NIOMDYLINGTIQQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.166
• 拓扑面积：
  72.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] DERIVATIVES OF [(3-HYDROXY-4 PYRON-2-YL)METHYL]-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS<br/>[FR] DÉRIVÉS DE [(3-HYDROXY-4 PYRON-2-YL)MÉTHYL]-AMINE ET LEURS UTILISATIONS EN TANT QUE MÉDICAMENTS ANTI-NÉOPLASIQUES
  申请人：UNIV DEGLI STUDI URBINO

  公开号：WO2010061282A1

  公开（公告）日：2010-06-03

  The present invention relates to compounds having general formula (I), i.e. poly- alkyl -bis -maltolic molecules and in particular to derivates of [ (3 -hydroxy- 4 -pyron- 2 -yl) methyl] -amine and pharmaceutically acceptable salts thereof, and to the use thereof as anti -neoplastic drugs, in particular, for the preparation of a medicament for the treatment of neoplastic diseases.

  本发明涉及具有一般式（I）的化合物，即聚烷基-双-麦芽酸分子，特别是[（3-羟基-4-吡喃-2-基）甲基]-胺及其药学上可接受的盐的衍生物，以及将其用作抗肿瘤药物，特别是用于制备治疗肿瘤疾病的药物。
• DERIVATIVE OF [(3-HYDROXY-4 PYRON-2-YL)-METHYL]-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS
  申请人：Fanelli Mirco

  公开号：US20120035255A1

  公开（公告）日：2012-02-09

  The present invention relates to compounds having general formula (I), i.e. poly-alkyl-bis-maltolic molecules and in particular to derivates of [(3-hydroxy-4-pyron-2-yl)methyl]-amine and pharmaceutically acceptable salts thereof, and to the use thereof as anti-neoplastic drugs, in particular, for the preparation of a medicament for the treatment of neoplastic diseases.

  本发明涉及具有一般式（I）的化合物，即聚烷基双麦芽酸分子，特别是[(3-羟基-4-吡啶-2-基)甲基]-胺及其药学上可接受的盐的衍生物，以及将其用作抗肿瘤药物，特别是用于制备治疗肿瘤疾病的药物。
• DERIVATIVES OF Ý(3-HYDROXY-4 PYRON-2-YL)METHYL¨-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS
  申请人：Universita Degli Studi Di Urbino

  公开号：EP2367809A1

  公开（公告）日：2011-09-28
• DERIVATIVES OF [(3-HYDROXY-4 PYRON-2-YL)METHYL]-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS
  申请人：Universita Degli Studi Di Urbino

  公开号：EP2367809B1

  公开（公告）日：2013-03-13
• PHARMACEUTICAL COMPOSITION OF [ (3-HYDROXY-4 -PYRON-2-YL) METHYL]-AMINE DERIVATIVES AND DNA DEMETHYLATING AGENTS AND THEIR USE AS ANTI-NEOPLASTIC DRUGS
  申请人：Università Degli Studi Di Urbino "Carlo Bo"

  公开号：EP3478282A1

  公开（公告）日：2019-05-08