(1R,3S,4S)-3-(benzylthio)-4-(tert-butyldimethylsilyloxy)cyclopentan-1-ol | 885612-76-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (1R,3S,4S)-3-(benzylthio)-4-(tert-butyldimethylsilyloxy)cyclopentan-1-ol
• CAS: 885612-76-0
• 化学式: C₁₈H₃₀O₂SSi
• 分子量: 338.587
• InChiKey: VNWAKPOHLTXQIP-IKGGRYGDSA-N

反应信息

• 作为反应物：
  描述：

  (1R,3S,4S)-3-(benzylthio)-4-(tert-butyldimethylsilyloxy)cyclopentan-1-ol 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 以87%的产率得到(1R,3S,4S)-4-(benzylthio)cyclopentane-1,3-diol
  参考文献：
  名称：

  Novel preparation of (−)-4-hydroxycyclohex-2-enone: reaction of 4-hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone with some thiols

  摘要：

  A new route to (R)-4-hydroxycyclohex-2-enone from cyclohexanedione monoketal (27% yield) commences with reaction of the ketal with nitrosobenzene catalysed by L-proline. 4-Hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone react with thiols to afford the corresponding syn-disubstituted cycloalkanones. (c) 2006 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetasy.2006.01.002
• 作为产物：
  描述：

  (S)-4-叔丁基二甲基硅氧基-2-环戊酮 在 sodium tetrahydroborate 、 cerium(III) chloride 、 三乙胺 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 23.25h， 生成 (1R,3S,4S)-3-(benzylthio)-4-(tert-butyldimethylsilyloxy)cyclopentan-1-ol
  参考文献：
  名称：

  Novel preparation of (−)-4-hydroxycyclohex-2-enone: reaction of 4-hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone with some thiols

  摘要：

  A new route to (R)-4-hydroxycyclohex-2-enone from cyclohexanedione monoketal (27% yield) commences with reaction of the ketal with nitrosobenzene catalysed by L-proline. 4-Hydroxycyclohex-2-enone and 4-hydroxycyclopent-2-enone react with thiols to afford the corresponding syn-disubstituted cycloalkanones. (c) 2006 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetasy.2006.01.002