7a-(4-(heptyloxy)phenethyl)tetrahydro-1H-oxazolo[3,4-c]oxazole | 1401420-97-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 7a-(4-(heptyloxy)phenethyl)tetrahydro-1H-oxazolo[3,4-c]oxazole
• 英文别名: 7a-[2-(4-Heptoxyphenyl)ethyl]-1,3,5,7-tetrahydro-[1,3]oxazolo[3,4-c][1,3]oxazole
• CAS: 1401420-97-0
• 化学式: C₂₀H₃₁NO₃
• 分子量: 333.471
• InChiKey: YPKKEFWUYMDOEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  24
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  30.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] NOVEL HETEROCYCLIC COMPOUNDS AS MODULATORS OF SPHINGOLIPID SIGNALING AND USES THEREOF<br/>[FR] NOUVEAUX COMPOSÉS HÉTÉROCYCLIQUES COMME MODULATEURS DE SIGNALISATION DES SPHINGOLIPIDES ET LEURS UTILISATIONS
  申请人：UNIV JW GOETHE FRANKFURT MAIN

  公开号：WO2012131096A1

  公开（公告）日：2012-10-04

  The present invention relates to new heterocyclic compounds as modulators of sphingolipid signaling and uses thereof as pharmaceutically active agents, suitable for treating proliferative, degenerative, infectious, and other diseases.

  本发明涉及新的杂环化合物，作为鞘脂信号调节剂和作为药物活性剂的用途，适用于治疗增殖性、退行性、感染性和其他疾病。
• Novel sphingolipid heterocyclic compounds as modulators of sphingolipid signaling and uses thereof
  申请人：Johann Wolfgang Goethe-Universität Frankfurt am Main

  公开号：EP2505589A1

  公开（公告）日：2012-10-03

  The present invention relates to new sphingolipid heterocyclic compounds as modulators of sphingolipid signaling and uses thereof as pharmaceutically active agents, suitable for treating proliferative, degenerative, infectious, and other diseases. wherein X is selected from a methylene group (CH2) and oxygen (O); and pharmaceutically acceptable salts thereof.

  本发明涉及新的鞘脂异环化合物，作为鞘脂信号调节剂和药用活性剂的用途，适用于治疗增殖性、退行性、感染性和其他疾病。其中X选自亚甲基基（CH2）和氧（O）；以及其药学上可接受的盐。
• Novel Heterocyclic Compounds as Modulators of Sphingolipid Signaling and Uses Thereof
  申请人：Stark Holger

  公开号：US20140100248A1

  公开（公告）日：2014-04-10

  The present invention relates to new heterocyclic compounds as modulators of sphingolipid signaling and uses thereof of as pharmaceutically active agents, suitable for treating proliferative, degenerative, infectious, and other diseases.