(Z)-3-iodobut-2-enoic acid diallylamide | 1194509-24-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-3-iodobut-2-enoic acid diallylamide
• CAS: 1194509-24-4
• 化学式: C₁₀H₁₄INO
• 分子量: 291.132
• InChiKey: ICTKDYKVUKELQB-HJWRWDBZSA-N

反应信息

• 作为产物：
  描述：

  but-2-ynoic acid diallylamide 在 aluminum (III) chloride 、 sodium iodide 、 水 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 18.0h， 以69%的产率得到(Z)-3-iodobut-2-enoic acid diallylamide
  参考文献：
  名称：

  AlCl3–NaI(NaBr)–t-BuOH: mild, chemo- and stereoselective reagents for hydrohalogenation of propiolic derivatives

  摘要：

  (Z)-beta-lodo-propenamides and -beta-iodo-propenoic esters were selectively prepared in high yields, at room temperature, through reaction of 2-propynamides and 2-propynoic esters, respectively, with AlCl3 and Nal in the presence of t-BuOH in dichloromethane. These experimental conditions are compatible with the presence of acid sensitive acetal groups. Alternative use of EtOH or H2O in place of t-BuOH was investigated. (Z)-Bromo-propenamides and corresponding esters were prepared according to a similar procedure using sodium bromide in refluxing acetonitrile. (C) 2009 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tet.2009.08.032