1-[diethoxy(methyl)silyl]-N-[[diethoxy(methyl)silyl]methyl]-N-methylmethanamine | 18551-79-6

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 1-[diethoxy(methyl)silyl]-N-[[diethoxy(methyl)silyl]methyl]-N-methylmethanamine
• CAS: 18551-79-6
• 化学式: C₁₃H₃₃NO₄Si₂
• 分子量: 323.58
• InChiKey: OUWXUPFUPXALHU-UHFFFAOYSA-N

物化性质

• 沸点：
  301.9±27.0 °C(Predicted)
• 密度：
  0.931±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.29
• 重原子数：
  20.0
• 可旋转键数：
  12.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.16
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  1-[diethoxy(methyl)silyl]-N-[[diethoxy(methyl)silyl]methyl]-N-methylmethanamine 、 苯酚 以 正庚烷 为溶剂， 反应 48.0h， 以41%的产率得到Methyl-bis-[(methyl-diphenoxy-silanyl)-methyl]-amine
  参考文献：
  名称：

  摘要：

  Previously unknown N,N-bis[ethoxy(methyl)silylmethyl]amines MeN[CH2SiMem(OEt)(3-m)]2 (m = 0-2) were synthesized. According to UV spectral data, only MeN[CH2SiMe2(OEt)](2) form hydrogen bond with phenol in a heptane solution. The amines with m = 0 and 1 fail to forms hydrogen bond with phenol [under the same conditions, N-(triethoxysilylmethyl)dimethylamine Me2NCH2Si(OEt)(3) forms a strong hydrogen bond with phenol]. All the amines (m = 0-2) enter transetherification with phenol to give compounds of the general formula MeN[CH2SiMem(OPh)(n)(OEt)(3-m-n)](2) (m = 0-2, n = 1-3). Refluxing of N,N-bis[ethoxy(methyl) silylmethyl]amines with excess phenol results in cleavage of the Si-C bond by phenol, providing phenoxy-silanes MemSi(OPh)(4-m) (m = 0-2) and trimethylamine.

  DOI：

  10.1023/a:1012387018984
• 作为产物：
  描述：

  (氯甲基)甲基二乙氧基硅烷 、 甲胺 反应 48.0h， 以43%的产率得到1-[diethoxy(methyl)silyl]-N-[[diethoxy(methyl)silyl]methyl]-N-methylmethanamine
  参考文献：
  名称：

  摘要：

  Previously unknown N,N-bis[ethoxy(methyl)silylmethyl]amines MeN[CH2SiMem(OEt)(3-m)]2 (m = 0-2) were synthesized. According to UV spectral data, only MeN[CH2SiMe2(OEt)](2) form hydrogen bond with phenol in a heptane solution. The amines with m = 0 and 1 fail to forms hydrogen bond with phenol [under the same conditions, N-(triethoxysilylmethyl)dimethylamine Me2NCH2Si(OEt)(3) forms a strong hydrogen bond with phenol]. All the amines (m = 0-2) enter transetherification with phenol to give compounds of the general formula MeN[CH2SiMem(OPh)(n)(OEt)(3-m-n)](2) (m = 0-2, n = 1-3). Refluxing of N,N-bis[ethoxy(methyl) silylmethyl]amines with excess phenol results in cleavage of the Si-C bond by phenol, providing phenoxy-silanes MemSi(OPh)(4-m) (m = 0-2) and trimethylamine.

  DOI：

  10.1023/a:1012387018984