Heptadecanoyl carnitine | 106182-29-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Heptadecanoyl carnitine
• 英文别名: 3-heptadecanoyloxy-4-(trimethylazaniumyl)butanoate
• CAS: 106182-29-0
• 化学式: C24H47NO4
• 分子量: 413.6
• InChiKey: DWSFAVOTORHAAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  29
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  66.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• BACTERIA ENGINEERED TO TREAT DISORDERS INVOLVING PROPIONATE CATABOLISM
  申请人：Synlogic, Inc.

  公开号：US20170216370A1

  公开（公告）日：2017-08-03

  The present disclosure provides engineered bacterial cells comprising a heterologous gene encoding a propionate catabolism enzyme. In another aspect, the engineered bacterial cells further comprise at least one heterologous gene encoding a transporter of propionate or a kill switch. The disclosure further provides pharmaceutical compositions comprising the engineered bacteria, and methods for treating disorders involving the catabolism of propionate, such as Propionic Acidemia and Methylmalonic Acidemia, using the pharmaceutical compositions.
• METHODS FOR SEQUENTIALLY PREPARING DIFFERENT TEST SAMPLES FROM A SINGLE DRIED BLOOD SAMPLE
  申请人：PerkinElmer Health Sciences, Inc.

  公开号：US20200283835A1

  公开（公告）日：2020-09-10

  Provided are processes for the use of a single dried blood sample for the preparation of test samples including targets of differing structures. The processes allow the same dried blood sample to be used for preparation of a first test sample including a non-nucleic acid target, and the same dried blood sample to be subsequently processed for preparation of a test sample that includes a nucleic acid target whereby the processes preserve the ability of the nucleic acid to be detected in subsequent detection assays following prior isolation of non-nucleic acid targets.