(+/-)-Ethyl-2-hydroxy-3-butynsaeure | 71693-23-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (+/-)-Ethyl-2-hydroxy-3-butynsaeure
• 英文别名: 2-Ethyl-2-hydroxybut-3-ynoic acid
• CAS: 71693-23-7
• 化学式: C₆H₈O₃
• mdl: MFCD19230518
• 分子量: 128.128
• InChiKey: RAISIVODIOAIKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Methods and compositions for determining the sequence of nucleic acid molecules
  申请人：——

  公开号：US20020119456A1

  公开（公告）日：2002-08-29

  Methods and compounds, including compositions therefrom, are provided for determining the sequence of nucleic acid molecules. The methods permit the determination of multiple nucleic acid sequences simultaneously. The compounds are used as tags to generate tagged nucleic acid fragments which are complementary to a selected target nucleic acid molecule. Each tag is correlative with a particular nucleotide and, in a preferred embodiment, is detectable by mass spectrometry. Following separation of the tagged fragments by sequential length, the tags are cleaved from the tagged fragments. In a preferred embodiment, the tags are detected by mass spectrometry and the sequence of the nucleic acid molecule is determined therefrom. The individual steps of the methods can be used in automated format, e.g., by the incorporation into systems.

  本发明提供了用于确定核酸分子序列的方法和化合物，包括从中制备的组合物。该方法允许同时确定多个核酸序列。该化合物被用作标签，以生成与所选目标核酸分子互补的标记核酸片段。每个标签与特定的核苷酸相关联，在一种优选实施方式中，可以通过质谱法检测到。在按顺序长度分离标记片段后，标签从标记片段中被切除。在一种优选实施方式中，标签通过质谱法被检测，从而确定核酸分子的序列。该方法的各个步骤可以在自动化格式中使用，例如通过纳入系统中。