Acetic acid 4-methylcyclohexylmethyl ester | 53075-43-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Acetic acid 4-methylcyclohexylmethyl ester
• 英文别名: (4-methylcyclohexyl)methyl acetate
• CAS: 53075-43-7
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.25
• InChiKey: WGJWXWQIHHQIRQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] 2-POLYCYCLIC PROPYNYL ADENOSINE ANALOGS HAVING A2A AGONIST ACTIVITY<br/>[FR] ANALOGUES DE 2-POLYCYCLIQUE PROPYNYLE ADENOSINE PRESENTANT UNE ACTIVITE AGONISTE DE A2A
  申请人：UNIV VIRGINIA

  公开号：WO2006023272A1

  公开（公告）日：2006-03-02

  The invention provides compounds having the following general formula (I) wherein X, R1, R2, R7 and Z are as described herein.

  这项发明提供了具有以下一般式(I)的化合物，其中X、R1、R2、R7和Z如本文所述。
• 2-polycyclic propynyl adenosine analogs having A2A agonist activity
  申请人：Rieger M. Jayson

  公开号：US20060040889A1

  公开（公告）日：2006-02-23

  The invention provides compounds having the following general formula (I): wherein X, R 1 , R 2 , R 7 and Z are as described herein.

  这项发明提供了具有以下一般式（I）的化合物： 其中X、R1、R2、R7和Z如本文所述。
• ALPHA-SUBSTITUTED VINYLTIN COMPOUND
  申请人：Tatsuta Kuniaki

  公开号：US20090023939A1

  公开（公告）日：2009-01-22

  To provide α-substituted vinyltin useful for the search for function-developing substances such as pharmaceuticals/agrichemicals and functional materials and for the construction of a compound library. An α-substituted vinyltin compound represented by the formula (1), a tautomer or salt of the compound or a solvate thereof: R 2 CH═C(R 3 )Sn(R 1 ) 3 (1) wherein R 1 is a C 1-10 alkyl group, a C 2-14 aryl group or the like, R 2 is a C 2-14 aryl group, a C 2-9 heterocyclyl group, a C 3-10 cycloalkyl group or the like, and R 3 is a carbamoyl group, a thiocarbamoyl group, an isocyanate group, an isothiocyanate group, a formylamino group, a thioformylamino group, an isonitrile group, an urea group, a carbamate group or the like.

  提供α-取代的乙烯基锡，用于寻找功能发展物质，如药物/农药和功能材料，以及用于构建化合物库。由下式表示的α-取代的乙烯基锡化合物（1）或其互变异构体或盐或溶剂合物：R2CH═C(R3)Sn(R1)3（1）其中R1是C1-10烷基，C2-14芳基或类似物，R2是C2-14芳基，C2-9杂环基，C3-10环烷基或类似物，R3是氨基甲酰基，硫氨基甲酰基，异氰酸酯基，异硫氰酸酯基，甲酰氨基基，硫代甲酰氨基基，异腈基，脲基，氨基甲酸酯基或类似物。
• [EN] INDUCTION OF PHARMACOLOGICAL STRESS WITH ADENOSINE RECEPTOR AGONISTS<br/>[FR] INDUCTION DE CONTRAINTE PHRAMACOLOGIQUE AU MOYEN D'AGONISTES DU RECEPTEUR DE L'ADENOSINE
  申请人：UNIV VIRGINIA

  公开号：WO2000078774A2

  公开（公告）日：2000-12-28

  A method is provided employing A 2a adenosine receptor agonists of formula (I) vasodilators to detect the presence and assess the severity of coronary artery stenosis.

  提供一种方法，使用公式（I）的A 2a腺苷受体激动剂作为血管扩张剂来检测冠状动脉狭窄的存在并评估其严重程度。
• Methods and compositions for treating inflammatory response
  申请人：University of Virginia Patent Foundation

  公开号：US20010027185A1

  公开（公告）日：2001-10-04

  Compounds and methods are provided to treat inflammatory conditions with certain A 2A adenosine receptor antagonists.

  提供了化合物和方法，用于使用特定的A2A腺苷受体拮抗剂治疗炎症病症。