opt.-inakt. 1-Methyl-4ξ-n-propyl-prolin | 2650-00-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: opt.-inakt. 1-Methyl-4ξ-n-propyl-prolin
• 英文别名: 1-methyl-4-propyl-pyrrolidine-2-carboxylic acid；1-Methyl-4-propylpyrrolidine-2-carboxylic acid
• CAS: 2650-00-2
• 化学式: C₉H₁₇NO₂
• 分子量: 171.239
• InChiKey: MAWGMRQFCUEYCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Novel lincomycin derivatives possessing antimicrobial activity
  申请人：Lewis G. Jason

  公开号：US20050043248A1

  公开（公告）日：2005-02-24

  Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

  新型的林可霉素衍生物被披露。这些林可霉素衍生物表现出抗菌活性。本发明的化合物可能对细菌，包括革兰氏阳性生物，表现出强效活性，并且可能是有用的抗微生物药剂。该化合物的合成和使用方法也被披露。
• Novel lincomycin derivatives possessing antibacterial activity
  申请人：Lewis G. Jason

  公开号：US20050215488A1

  公开（公告）日：2005-09-29

  Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

  新型的林可霉素衍生物已被披露。这些林可霉素衍生物表现出抗菌活性。本发明的化合物可能对细菌，包括革兰氏阳性生物，表现出强效活性，并可能是有用的抗微生物药剂。该化合物的合成和使用方法也已被披露。
• ANTIBIOTIC COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT
  申请人：DEVLIN Brid

  公开号：US20080033031A1

  公开（公告）日：2008-02-07

  Antibiotic compounds and compositions and methods for the treatment of dermatological conditions including a sulfoxide or sulfone derivative of an antibiotic from the lincomycin family of antibiotics, or pharmaceutically acceptable salts thereof, optionally including a peroxide component.

  抗生素化合物和组合物以及治疗皮肤病的方法，包括来自林可霉素类抗生素的亚砜或磺酰基衍生物或其药学上可接受的盐，可选地包括过氧化物组分。
• NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY
  申请人：Vicuron Pharmaceuticals, Inc.

  公开号：EP1644393A2

  公开（公告）日：2006-04-12
• LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY
  申请人：Vicuron Pharmaceuticals, Inc.

  公开号：EP1654268A2

  公开（公告）日：2006-05-10