1,1,2,2,4,4,4-Heptafluorobutyl prop-2-enoate | 51053-31-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,1,2,2,4,4,4-Heptafluorobutyl prop-2-enoate
• CAS: 51053-31-7
• 化学式: C₇H₅F₇O₂
• 分子量: 254.1
• InChiKey: VWYCVZXPYHGXNI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  9

文献信息

• [EN] COMPOUNDS FOR OPTICALLY ACTIVE DEVICES<br/>[FR] COMPOSÉS POUR DISPOSITIFS OPTIQUEMENT ACTIFS
  申请人：MERCK PATENT GMBH

  公开号：WO2020212543A1

  公开（公告）日：2020-10-22

  The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive unit, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalmic devices.

  本发明涉及包含光活性单元的聚合化合物的创新眼科设备，所述聚合化合物，以及特别适合用于组合物和眼科设备的特殊单体化合物。
• [EN] AZACOUMARIN AND AZATHIOCOUMARIN DERIVATIVES FOR USE IN OPTICALLY ACTIVE DEVICES<br/>[FR] DÉRIVÉS D'AZACOUMARINES ET D'AZATHIOCOUMARINE DESTINÉS À ÊTRE UTILISÉS DANS DES DISPOSITIFS OPTIQUEMENT ACTIFS
  申请人：MERCK PATENT GMBH

  公开号：WO2021233800A1

  公开（公告）日：2021-11-25

  The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive chromophore, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalmic devices. The present invention is also directed to a process of changing the optical properties of said ophthalmic device or a precursor article for manufacturing said ophthalmic device.

  本发明涉及包括聚合物化合物的新型眼科器件，所述聚合物化合物包括光活性色素，以及特殊单体化合物，特别适用于眼科器件的组合物和眼科器件。本发明还涉及一种改变所述眼科器件的光学性能或用于制造所述眼科器件的前体物品的方法。
• POLYURETHANE (METH) ACRYLATES USING MODIFIED HYDROXYTHIOLS
  申请人：Dymax Oligomers and Coatings LLC

  公开号：US20150232422A1

  公开（公告）日：2015-08-20

  The invention provides intermediates of the formula: as well as a method of their preparation by reacting a thiol having at least two hydroxyl groups with a mono-unsaturated organic compound in the presence of a base catalyst. A polymerizable urethane acrylate oligomer or urethane methacrylate oligomer is formed by reacting a polyisocyanate with the intermediate. The polymerizable urethane acrylate oligomer or urethane methacrylate is blended with a polymerization initiator to form a composition which is useful in such applications as adhesives.

  本发明提供了以下式的中间体：以及通过在碱催化剂存在下将至少具有两个羟基的硫醇与一种单不饱和有机化合物反应制备它们的方法。通过将聚异氰酸酯与该中间体反应，形成可聚合的脲基丙烯酸酯低聚物或脲基甲基丙烯酸酯低聚物。将可聚合的脲基丙烯酸酯低聚物或脲基甲基丙烯酸酯与聚合引发剂混合，形成一种在粘合剂等应用中有用的组合物。
• Anionic polymers as toxin binders
  申请人：GelTex Pharmaceuticals, Inc.

  公开号：US20010041171A1

  公开（公告）日：2001-11-15

  The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of pendant acid functional groups which are directly attached to the polymer backbone or attached to the polymer backbone by a spacer group. The spacer group can have a length in the range from 0 to about 20 atoms. The toxin is, typically, an exotoxin secreted by a pathogenic microorganism, such as a bacterium.

  本发明涉及一种通过向动物（例如人类）施用具有多个挂链酸性官能团的聚合物的治疗有效量来抑制动物中毒素的方法。这些酸性官能团可以直接连接到聚合物骨架上，也可以通过一个间隔基团连接到聚合物骨架上。间隔基团的长度可以在0到约20个原子的范围内。毒素通常是由病原微生物（例如细菌）分泌的外毒素。
• IONIC POLYMERS AS TOXIN-BINDING AGENTS
  申请人：GelTex Pharmaceuticals, Inc.

  公开号：US20040009145A1

  公开（公告）日：2004-01-15

  A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the polymer backbone. The polymer can be a homopolymer or a copolymer. In one embodiment, the polymer is a copolymer comprising a monomer having a pendant ammonium group and a hydrophobic monomer.

  一种用于治疗哺乳动物（如人类）中的病原毒素的方法，包括使用具有阳离子基团附着在聚合物骨架上的治疗有效量的聚合物来治疗哺乳动物。该聚合物可以是同聚物或共聚物。在一种实施例中，该聚合物是一种共聚物，包括具有挂链铵基和疏水单体的单体。