2-ethoxy-6-[(2-piperidin-1-ylethylimino)methyl]phenol | 1246637-55-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-ethoxy-6-[(2-piperidin-1-ylethylimino)methyl]phenol
• 英文别名: 2-ethoxy-6-(2-piperidin-1-ylethyliminomethyl)phenol
• CAS: 1246637-55-7
• 化学式: C₁₆H₂₄N₂O₂
• 分子量: 276.379
• InChiKey: LNAFNEJEOPCGEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  20
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  45.1
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-ethoxy-6-[(2-piperidin-1-ylethylimino)methyl]phenol 、 zinc dibromide 以 甲醇 为溶剂， 以61%的产率得到dibromo(2-ethoxy-6-[(2-piperidin-1-ylethylimino)methyl]phenol)zinc(II)
  参考文献：
  名称：

  Synthesis and crystal structures of Schiff base zinc(III) complexes with antibacterial activity

  摘要：

  Two halide-coordinated zinc(II) complexes with the Schiff base 2-ethoxy-6-[(2-piperidin-1-ylethylimino)methyl]phenol were synthesized and structurally characterized by elemental analysis (C, H, N), FT-IR spectra, and single-crystal X-ray diffraction. The Zn atom in each complex is four-coordinated in a tetrahedral geometry by one phenolic O and one imine N atoms of the Schiff base ligand and by two halide atoms. The antibacterial activity of the complexes and the Schiff bases against the bacteria Staphylococcus aureus, Bacillus anthracis, Pseudomonas aeruginosa, and Streptococcus agalactiae was investigated.

  DOI：

  10.1134/s1070328410070067