O-[（N-琥珀酰亚胺基）琥珀酰基-氨基乙基]-O'-甲基聚乙二醇2'000 | 92451-00-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: O-[（N-琥珀酰亚胺基）琥珀酰基-氨基乙基]-O'-甲基聚乙二醇2'000
• 英文名称: O-((N-Succinimidyl)succinyl-aminoethyl)&
• 英文别名: (2,5-dioxopyrrolidin-1-yl) 4-[2-(2-methoxyethoxy)ethylamino]-4-oxobutanoate
• CAS: 92451-00-8
• 化学式: C₁₃H₂₀N₂O₇
• 分子量: 316.31
• InChiKey: HDBVCBKJSCYANJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  22
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  111
• 氢给体数：
  1
• 氢受体数：
  7

安全信息

• WGK Germany：
  3

文献信息

• Neuropeptide-2 receptor (Y-2R) agonists and uses thereof
  申请人：Conde-Knape Karin

  公开号：US20070135351A1

  公开（公告）日：2007-06-14

  Provided herein are neuropeptide-2 receptor agonists of the formula (I): as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.

  本文提供了公式（I）的神经肽2受体激动剂，以及其药学上可接受的盐，衍生物和片段，其中取代基如规范中所披露的那样。这些化合物及其包含它们的制药组合物可用于治疗肥胖症和糖尿病等疾病。
• GLUCOSE-DEPENDENT INSULINOTROPIC PEPTIDE ANALOGS
  申请人：Danho Waleed

  公开号：US20120101037A1

  公开（公告）日：2012-04-26

  The present invention provides compounds which are analogs of glucose-dependent insulinotropic polypeptide (GIP) and pharmaceutically acceptable salts of such compounds. These compounds have activity as agonists of GIP receptor.
• METHOD FOR APPLYING A COATING TO A POLYMERIC SUBSTRATE
  申请人：SOPHION BIOSCIENCE A/S

  公开号：US20150240115A1

  公开（公告）日：2015-08-27

  A single-step method for applying a coating to a polymeric substrate comprising: exposing a photoreactive compound and a polymeric compound in an aqueous solvent to ultraviolet radiation in the presence of said polymeric substrate to obtain a covalently bound coating thereon comprising a reaction product of the photoreactive compound and the polymeric compound. More particularly, the present invention relates to a method of applying a coating to a polymeric substrate in order to reduce the adsorption of analytes in solution to said substrate by imparting properties to the substrate similar to the properties of the coating applied.
• US7642244B2
  申请人：——

  公开号：US7642244B2

  公开（公告）日：2010-01-05
• US9023986B2
  申请人：——

  公开号：US9023986B2

  公开（公告）日：2015-05-05