9,10-dioxa-syn-(methylthiomethyl,methyl)bimane | 76421-81-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并吡唑类
• 英文名称: 9,10-dioxa-syn-(methylthiomethyl,methyl)bimane
• 英文别名: 2,6-Dimethyl-1,7-bis(methylsulfanylmethyl)pyrazolo[1,2-a]pyrazole-3,5-dione
• CAS: 76421-81-3
• 化学式: C₁₂H₁₆N₂O₂S₂
• 分子量: 284.403
• InChiKey: BCAWUMHWRGMLDG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  91.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  3,5-双溴甲基-2,6-二甲基吡唑并[1,2-a]吡唑-1,7-二酮 、 sodium thiomethoxide 以 乙醇 为溶剂， 反应 3.0h， 以58%的产率得到9,10-dioxa-syn-(methylthiomethyl,methyl)bimane
  参考文献：
  名称：

  Bimanes. 6. Reactive halogen derivatives of syn- and anti-1,5-diazabicyclo[3.3.0]octadienediones (9,10-dioxabimanes)

  摘要：

  DOI：

  10.1021/jo00321a029

文献信息

• DIMERIZER COMPOUND
  申请人：AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

  公开号：US20160297820A1

  公开（公告）日：2016-10-13

  There is provided a compound comprising at least two ligands that are individually coupled to a linker, wherein each ligand is independently selected from the group consisting of a substituted benzylguanine derivative, a substituted benzylcytosine derivative, a haloalkyl moiety, a drug, a peptide, a hormone, an inorganic compound and a protein. The compound may be part of an oligomer. The compound may be employed in a method of dimerizing a pair of proteins, which may alter a biological function in a cell. There is also provided a method of forming the compound.