| 106210-86-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 106210-86-0
• 化学式: C₂₆H₂₂Cl₂P₂Pd
• 分子量: 573.734
• InChiKey: WDRXIBCIQRPXKJ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  31.0
• 可旋转键数：
  4.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  在 C₂H₅OH 、 catalyst: N(CH₂CH₃)3 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Use of Michael additions to (Ph₂P)₂CCH₂complexes to prepare thiophene- and pyrrole-functionalised metal–phosphine complexes

  摘要：

  The complex [Pd(O2CMe)2(vdpp)] la [vdpp = (Ph2P)2C=CH2] undergoes nucleophilic addition at the double bond with primary alcohols to afford [Pd(O2CMe)2{(Ph2P)2CHCH2OR}] 2 [R = Me, Et, CH2CH2C4H3S-3 or CH2C6H3(OMe)2-3,4]. These were not isolated pure, but metathesis with NaI gave the corresponding diiodides 3, which were isolated, and have been fully characterised by microanalysis and infrared and NMR (H-1 and P-31-{H-1}) spectroscopies. By using 2- (3-thienyl)ethanol as the nucleophile, the complex [PdI2{(Ph2P)2CHCH2OCH2CH2C4H3S-3)] 3c was obtained, and its electrochemistry examined. The reactivity of the double bond in 1a towards other potential weak nucleophiles has been examined. In particular, pyrrole underwent electrophilic addition with la to give, after work-up with NaI, [PdI2{(Ph2P)2CHCH2C4H3NH}]4b. Proton NMR spectroscopy established that 4b was a mixture of 2- and 3-pyrrole isomers (ca. 3: 1). The complexes [MCl2(vdpp)] (M = Pd 1c or Pt 1d) were less reactive, but underwent addition with alcohols in the presence of NEt3 as catalyst to afford [MCl2{(Ph2P)2CHCH2OR}] (M = Pd 5 or Pt 6, R = Et or CH2CH2C4H3S-3). The complex [Pt(vdpp)2][PF6]2 7 has been prepared from [PtCl2(PhCN)2], vdpp and AgPF6 in dichloromethane-acetonitrile. Details of the reaction of 7 with 2- (3-thienyl)ethanol are given. The crystal structure of 3c has been determined.

  DOI：

  10.1039/dt9920003403

文献信息

• The high activation of (Ph₂P)₂CCH₂by palladium acetate or palladium chloride towards additions
  作者：Andrew M. Herring、Simon J. Higgins、Grant B. Jacobsen、Bernard L. Shaw

  DOI：10.1039/c39860000882

  日期：——

  Palladium acetate very highly activates co-ordinated (Ph2P)2CCH2 towards additions of amines, hydrazines, amino acid esters, alcohols, phenols, thiols, acetylacetone, and acetoacetic ester; palladium chloride also activates but less strongly: additionally, Pd(OAc)2 catalyses additions to the free ligand (Ph2P)2CCH2.

  醋酸钯对配位的 (Ph2P)2CCH2 有很强的活化作用，可用于胺、肼、氨基酸酯、醇、酚、硫醇、乙酰丙酮和乙酰乙酸酯的加成；氯化钯也有活化作用，但不太强烈：此外，Pd(OAc)2 还能催化游离配体 (Ph2P)2CCH2 的加成。