4-chloro-2-nitro-benzenesulfenic acid amide | 5147-67-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-chloro-2-nitro-benzenesulfenic acid amide
• 英文别名: 4-Chlor-2-nitro-benzolsulfensaeure-amid；4-Chlor-2-nitro-benzolsulfenamid；S-(4-Chlor-2-nitro-phenyl)-thiohydroxylamin；4-Chlor-2-nitro-phenylschwefelamid；S-(4-chloro-2-nitrophenyl)thiohydroxylamine
• CAS: 5147-67-1
• 化学式: C₆H₅ClN₂O₂S
• 分子量: 204.637
• InChiKey: FUXOZFIMMJKNED-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  97.1
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-chloro-2-nitro-benzenesulfenic acid amide 在 溶剂黄146 作用下， 生成 bis-(4-chloro-2-nitro-benzenesulfenyl)-amine
  参考文献：
  名称：

  Zincke, Justus Liebigs Annalen der Chemie, 1918, vol. 416, p. 103

  摘要：

  DOI：
• 作为产物：
  描述：

  4-chloro-2-nitrobenzenesulfenyl chloride 在 氯仿 、 氨 作用下， 生成 4-chloro-2-nitro-benzenesulfenic acid amide
  参考文献：
  名称：

  Zincke, Justus Liebigs Annalen der Chemie, 1918, vol. 416, p. 103

  摘要：

  DOI：

文献信息

• COMPLICATIONS OF VASCULAR ACCESS: RESULTS OF A EUROPEAN MULTI CENTRE STUDY OF THE EDTNA/ERCA RESEARCH BOARD
  作者：Monique M. Elseviers、Jean-Pierre Waeleghem

  DOI：10.1111/j.1755-6686.2003.tb00301.x

  日期：2003.7.9

  SUMMARYThe pilot project of the Research Board of EDTNA/ERCA handled the management of vascular accesses (VA) in European dialysis centres. In the first part of the study, centre policies related to VA management were investigated. In the second part of the study, individual patients were followed prospectively during one year. This paper reports on several topics of the second part of the project, investigating complications of the VA related to centre, patient characteristics and dialysis techniques. used.Complications most frequently observed were thrombosis, stenosis, infection, bleeding and flow problems. Gradually more infections and flow problems were observed if the centre size and the patients/nurse ratio went up.Complication rate was not significantly influenced by age, gender, renal diagnosis, time on dialysis or medication used by the patient. In contrast, the number of vascular accesses in the past and interventions in the VA before first use resulted in an increased number of complications.Nurses have a key role in the prevention, manipulation and outcome of vascular access related complications.